Gender and Age Dependent Bacteriological Etiology of Community-Acquired Blood Stream Infection

Bangladesh Journal of Medical Microbiology Pub Date : 2023-10-10 DOI:10.3329/bjmm.v17i1.68127

Nafisa Rashid, Ritu Shaha, Md Mahbubur Rahman, Nasrin Akhter Maya, Asma Ul Hosna

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Abstract

Background: Bloodstream infection constitutes one of the most serious situations in infectious disease. Objective: The purpose of the presents study was to determine the gender and age dependent etiology of community- acquired urinary blood stream infection. Methodology: This was a retrospective analysis of blood samples from clinically suspected cases of blood stream infection. Samples were collected at Ad-din Women’s Medical College Hospital, Dhaka & Rushmono Specialized Hospital, Dhaka from January 2018 to September 2018. All the samples were collected from inpatient’s and outpatient’s department of our hospital during the study period and processed in Microbiology laboratory. The BD BACTEC FX40 automated blood culture method was used to isolate bacterial pathogens and antimicrobial susceptibility test was performed by Kirby-Bauer disc diffusion method. Results: A total of 483 (16.1%) pathogens were isolated from 3018 bacteremia suspect patient blood specimens. Gram-negative cocci (58.4%) were predominant organisms recovered followed by Gram-positive bacilli (41.6%). Majority of BSI were caused by Gram negative bacteria predominantly Salmonella Typhi (31.1%). Salmonella species was found less prevalent in the children (55%) and more frequent in the age groups 16 to 30 years (85.0%) and more than 60 years (100.0%). Acinetobacter species was found less prevalent in age group 16 to 30 years (7.5%). Escherichia coli was found only few prevalent in the 1 to 15 (0.5%) and higher frequent in the age groups 16 to 30 years (2.5%). Salmonella species isolates appeared to be sensitive to ceftriaxone (91.3%), meropenem (90.7%) and cotrimoxazole (76%). Sensitivity rates of ciprofloxacin, gentamycin and levofloxacin were 87.3% for coagulase-negative Staphylococcus species (CoNS). Conclusion: Both patients’ age and gender are significant factors in determining bloodstream infection. Bangladesh Journal of Medical Microbiology, January 2023;17(1):3-9

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社区获得性血流感染的性别和年龄相关性细菌学病因学研究

背景:血流感染是传染病中最严重的情况之一。目的:探讨社区获得性尿血流感染的性别和年龄依赖性病因学。方法:回顾性分析临床疑似血流感染病例的血液样本。样本在达卡的Ad-din妇女医学院医院收集;拉什莫诺专科医院，达卡，2018年1月至2018年9月。所有样本均于研究期间在我院住院部和门诊部采集，并在微生物实验室进行处理。采用BD BACTEC FX40全自动血培养法分离病原菌，采用Kirby-Bauer圆盘扩散法进行药敏试验。结果:3018例疑似菌血症患者血样中共检出病原菌483株(16.1%)。革兰氏阴性球菌占58.4%，其次是革兰氏阳性杆菌占41.6%。以革兰氏阴性菌为主，以伤寒沙门菌为主(31.1%)。沙门氏菌在儿童中的流行率较低(55%)，而在16 ~ 30岁年龄组(85.0%)和60岁以上年龄组(100.0%)中较常见。不动杆菌种类在16至30岁年龄组中较少流行(7.5%)。大肠杆菌在1至15岁人群中很少流行(0.5%)，而在16至30岁年龄组中发病率较高(2.5%)。沙门氏菌对头孢曲松(91.3%)、美罗培南(90.7%)和复方新诺明(76%)敏感。环丙沙星、庆大霉素和左氧氟沙星对凝固酶阴性葡萄球菌(con)的敏感性为87.3%。结论:年龄和性别是决定血流感染的重要因素。孟加拉医学微生物学杂志，2023年1月;17(1):3-9

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Bangladesh Journal of Medical Microbiology

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