Colonizer to Pathogen: A review on Enterococcal urinary tract infections

Rituparna Saha, Manisha Khandait, Moumita Sardar, Mukesh Sharma
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引用次数: 0

Abstract

Abstract Enterococcus species has been historically known as part of the commensal flora of the normal human alimentary tract. Implicated in a wide array of illnesses encompassing bloodstream infections, urinary tract infections, wound infections as well as intra-abdominal infections, it has been rapidly emerging as a pathogen of interest owing to its propensity to acquire multidrug resistance. Due to the high antibiotic pressure in healthcare settings and salient intrinsic resistance to commonly used classes of antimicrobials, Enterococcus selectively proliferates in nosocomial settings. Their hardy nature and ability to resist a wide array of disinfectants enable them to proliferate on surfaces as well as provide for efficient transmission in hospital settings. Since Urinary tract infection (UTI) is one of the commonest infections caused by Enterococcus species. We attempt to comprehensively overview the paradigm shift of this erstwhile colonizer to one of the common uropathogen in hospital and community settings.
病原体的定植者:肠球菌性尿路感染的研究进展
摘要肠球菌一直被认为是正常人类消化道共生菌群的一部分。它与血液感染、尿路感染、伤口感染和腹腔内感染等一系列疾病有关,由于其具有获得多药耐药性的倾向,它已迅速成为一种令人感兴趣的病原体。由于医疗环境中的高抗生素压力和对常用抗菌素的显著内在耐药性,肠球菌在医院环境中选择性增殖。它们的耐寒性和抵抗多种消毒剂的能力使它们能够在表面上增殖,并在医院环境中有效传播。尿路感染(UTI)是肠球菌引起的最常见感染之一。我们试图全面概述这种过去的殖民者在医院和社区环境中常见的尿路病原体之一的范式转变。
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6 weeks
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