{"title":"A feasibility study of 70 kV double low-dose coronary imaging technique in abdomen-fatty patients using dual-source CT","authors":"Lei Chen, Shang Ge, Yuan Chen, Ting-Ting Zhang, Ting-Ting Zhang, Zhao-Huan Zhu","doi":"10.4314/ahs.v23i3.70","DOIUrl":null,"url":null,"abstract":"Objective: To investigate the aplication of low contrast agent concentration and low tube voltage in coronary CTA on patientswith high BMI (26kg/m2<BMI≤28kg/m2) and ultra-high BMI (BMI>28kg/m2).
 Methods: 60 patients with high BMI (26kg/m2<BMI≤28kg/m2) and 60 patients with ultra-high BMI (BMI>28kg/m2) wererandomly divided into two groups: double low group A (n=30, tube voltage = 70 KV), double low group B (n=30, tube voltage= 70 KV), processed by SAFIRE iterative reconstruction with 270 mgI/ml contrast agent. Conventional group a (n=30, tubevoltage = 120 KV), conventional group b (n=30, tube voltage = 120 KV), with filtered back projection (FBP) and 370 mg I/mlcontrast agent. the image excellent index (FOM), the effective radiation dose (ED), mean CT value, signal-to-noise ratio (SNR),and contrast-to-noise ratio(CNR) between corresponding groups were compared.
 Result: There was no significant difference in subjective scores of coronary artery image quality between the two high BMIsubgroups (P>0.05).The ED of group A (1.103±0.101 mSv) was significantly lower than that of group a (4.663±0.412 mSv)(P<0.001).There was no significant difference in mean CT value, SNR and CNR between the two subgroups (P>0.05).The imageexcellent index (FOM) of group A was higher than that of group a (P<0.05).The total iodine content and iodine injectionrate in group A were lower than those in group a (P<0.001).The difference of subjective scores of coronary artery image qualitybetween the two ultra-high subgroups was significant. The mean CT value, SNR and CNR of group B were lower than those ofgroup b (P<0.05). The images of 14 patients in group B could not meet the diagnosis demand.
 Conclusion: It is feasible to reduce the tube voltage to 70KV in patients with abdominal BMI with high BMI (26Kg/m2<BMI≤28Kg/m2). For patients with abdominal obesity with ultra-high BMI (BMI>28Kg/m2), under the same conditions, the70KV can not meet the daily diagnosis requirement.
 Keywords: Radiation dose; tomography; coronary artery; iterative reconstruction; contrast agent; abdominal obesity.","PeriodicalId":7853,"journal":{"name":"African Health Sciences","volume":"17 1","pages":"0"},"PeriodicalIF":0.8000,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"African Health Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4314/ahs.v23i3.70","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: To investigate the aplication of low contrast agent concentration and low tube voltage in coronary CTA on patientswith high BMI (26kg/m228kg/m2).
Methods: 60 patients with high BMI (26kg/m228kg/m2) wererandomly divided into two groups: double low group A (n=30, tube voltage = 70 KV), double low group B (n=30, tube voltage= 70 KV), processed by SAFIRE iterative reconstruction with 270 mgI/ml contrast agent. Conventional group a (n=30, tubevoltage = 120 KV), conventional group b (n=30, tube voltage = 120 KV), with filtered back projection (FBP) and 370 mg I/mlcontrast agent. the image excellent index (FOM), the effective radiation dose (ED), mean CT value, signal-to-noise ratio (SNR),and contrast-to-noise ratio(CNR) between corresponding groups were compared.
Result: There was no significant difference in subjective scores of coronary artery image quality between the two high BMIsubgroups (P>0.05).The ED of group A (1.103±0.101 mSv) was significantly lower than that of group a (4.663±0.412 mSv)(P<0.001).There was no significant difference in mean CT value, SNR and CNR between the two subgroups (P>0.05).The imageexcellent index (FOM) of group A was higher than that of group a (P<0.05).The total iodine content and iodine injectionrate in group A were lower than those in group a (P<0.001).The difference of subjective scores of coronary artery image qualitybetween the two ultra-high subgroups was significant. The mean CT value, SNR and CNR of group B were lower than those ofgroup b (P<0.05). The images of 14 patients in group B could not meet the diagnosis demand.
Conclusion: It is feasible to reduce the tube voltage to 70KV in patients with abdominal BMI with high BMI (26Kg/m228Kg/m2), under the same conditions, the70KV can not meet the daily diagnosis requirement.
Keywords: Radiation dose; tomography; coronary artery; iterative reconstruction; contrast agent; abdominal obesity.
期刊介绍:
The African Health Sciences is an internationally refereed journal publishing original articles on research, clinical practice, public health, policy, planning, implementation and evaluation, in the health and related sciences relevant to Africa and the tropics. Its objectives are to: Advocate for and promote the growth of reading culture in sub Saharan Africa; Provide a high quality journal in which health and policy and other researchers and practitioners in the region can and world wide, can publish their work; Promote relevant health system research and publication in the region including alternative means of health care financing, the burden of and solution of health problems in marginalized urban and rural communities amongst the displaced and others affected by conflict; Promote research and the systematic collection and collation and publication of data on diseases and conditions of equity and influence; Promote development of evidence-based policies and guidelines for clinical, public health and other practitioners. African Health Sciences acknowledges support provided by the African Health Journals Partnership Project that is funded by the US National Institutes of Health (through the National Library of Medicine and the Fogarty International Center) and facilitated by the Council of Science Editors.