Restless legs syndrome in chronic renal failure patients on dialysis

IF 0.8 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

African Health Sciences Pub Date : 2023-10-11 DOI:10.4314/ahs.v23i3.88

Carin Behrens van Tonder, Gina Joubert, Anand Moodley

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引用次数: 0

Abstract

Background: Restless legs syndrome (RLS) occurs in patients with chronic renal failure (CRF). Objectives: To determine the prevalence and morbidity of RLS in CRF patients on dialysis. Methods: This cross-sectional questionnaire-based study included 100 dialysis patients (50 on haemodialysis [HD]; 50 on peritonealdialysis [PD]). A focused lower limb examination was done. Patients were classified with RLS when reporting uncomfortablefeelings in their legs that improved with movement and worsened when resting and at night. Results: Gender distribution was equal. The median age was 43 (19–67) years. Six patients (HD and PD n=3 each) had internationalcriteria-confirmed RLS. Twenty-four patients reported symptoms suggestive of RLS. Fourteen and 16 patients with RLSsymptoms were on HD and PD, respectively. Sleep disturbances occurred in 43.3% (n=13) of patients with RLS symptoms,compared to 20.0% (n=20) of the large cohort. Sleep disturbances, peripheral sensory loss, chronic disease-related anaemia,increased urea and decreased albumin levels were more common among patients with RLS symptoms. Conclusion: RLS symptoms occurred in 30.0% of the entire cohort, although only 6.0% met the international criteria. The typeof dialysis had no impact on the incidence of symptoms. Identifying RLS in patients with CRF on dialysis will allow for earlyintervention. Keywords: Restless legs syndrome; chronic renal failure; haemodialysis; peritoneal dialysis; symptoms.

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不宁腿综合征在慢性肾衰竭患者透析中的应用

背景:不宁腿综合征(RLS)发生于慢性肾功能衰竭(CRF)患者。目的:了解CRF透析患者RLS的患病率和发病率。方法:本研究以横断面问卷为基础，纳入100例透析患者(50例血液透析[HD];50例腹腔透析[PD])。行下肢集中检查。当患者报告腿部不舒服的感觉时，患者被归类为RLS，这种不舒服的感觉随着运动而改善，在休息和夜间时恶化。结果:性别分布相等。中位年龄为43岁(19-67岁)。6例(HD和PD各3例)有国际标准确认的RLS。24例患者报告有RLS症状。有rls症状的HD和PD患者分别为14例和16例。有RLS症状的患者中有43.3% (n=13)出现睡眠障碍，而在大队列中有20.0% (n=20)出现睡眠障碍。睡眠障碍、外周感觉丧失、慢性疾病相关性贫血、尿素升高和白蛋白水平降低在RLS患者中更为常见。结论:整个队列中有30.0%出现了RLS症状，但只有6.0%符合国际标准。透析类型对症状发生率无影响。识别CRF透析患者的RLS将有助于早期干预。关键词:不宁腿综合征;慢性肾衰竭;血液透析;腹膜透析;症状。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

African Health Sciences MEDICINE, GENERAL & INTERNAL-

CiteScore

2.30

自引率

0.00%

发文量

179

审稿时长

>12 weeks

期刊介绍： The African Health Sciences is an internationally refereed journal publishing original articles on research, clinical practice, public health, policy, planning, implementation and evaluation, in the health and related sciences relevant to Africa and the tropics. Its objectives are to: Advocate for and promote the growth of reading culture in sub Saharan Africa; Provide a high quality journal in which health and policy and other researchers and practitioners in the region can and world wide, can publish their work; Promote relevant health system research and publication in the region including alternative means of health care financing, the burden of and solution of health problems in marginalized urban and rural communities amongst the displaced and others affected by conflict; Promote research and the systematic collection and collation and publication of data on diseases and conditions of equity and influence; Promote development of evidence-based policies and guidelines for clinical, public health and other practitioners. African Health Sciences acknowledges support provided by the African Health Journals Partnership Project that is funded by the US National Institutes of Health (through the National Library of Medicine and the Fogarty International Center) and facilitated by the Council of Science Editors.