The Impact of SARS-CoV-2 Virus on Acute Coronary Syndrome Patients Correlated with Clinical, Echocardiographic and Coronary Angiographic Outcome

Abstract

Background; COVID-19 pandemic has led to many negative problems for all aspects of society. While respiratory symptoms are typically most severe manifestations of COVID-19 infection, SARS-CoV-2 infection may be responsible for diversity of potentially severe cardiovascular manifestations, mainly in studied cases with pre-existing cardiovascular conditions, Aim and objectives; to evaluate impact of SARS-CoV-2 virus on acute coronary syndrome patients and correlate it with clinical presentation, Echocardiography and coronary angiography outcome, Subjects & techniques: This was case control research, has been happened in Department of cardiology Al-Azhar University on 300 patients divided on three groups presented with acute coronary syndrome, STEMI and NSTEMI. First control group were presented only with STEMI. The second case under study group was presented by STEMI & SARS-CoV-2 active infection. The last group were presented by “NSTEMI or unstable angina” and SARS-CoV-2 active infection, Results; statistical analysis of 300 patients divided on three groups presented with acute coronary syndrome (STEMI, NSTEMI or unstable angina).That showed high variation among studied groups as regard EF (Ejection fraction), cardiogenic shock, respiratory failure and increased in-hospital mortality, Conclusion; In studied cases infected with SARS-CoV-2, acute myocardial injury is related to in-hospital mortality and is indicator of poor prognosis. careful indication of more invasive diagnostic tests and subsequent implementation of appropriate treatments without delay as time is muscle,