Peritoneal and Serum or Plasma Interleukin-6 as Early Biomarkers for Colorectal Anastomotic Leakage after Colorectal Surgery in Patients with Colorectal Cancer: A Systematic Review and Meta-Analysis

Q4 Medicine

Surgery, Gastroenterology and Oncology Pub Date : 2023-01-01 DOI:10.21614/sgo-582

Lucia Villegas-Coronado, Jose Lopez-Navarro, Diego Chavez-Bermudez, Ivan Gonzalez-Jimenez, Lucero Chao-Zhou, Dany Gonzalez-Bojorquez

引用次数: 0

Abstract

Background: The early detection of colorectal anastomotic leakage (CAL) remains challenging despite advancements in diagnostic methods. Reliable markers are needed to reduce patient morbidity and mortality. Cytokines in drain fluid and systemic cytokine levels have shown potential as predictive markers for CAL, but more robust evidence is required. This systematic review and meta-analysis aimed to evaluate the importance of peritoneal and serum or plasma interleukin-6 (IL-6) levels in the early detection of CAL after colorectal surgery in colorectal cancer patients.

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腹膜和血清或血浆白细胞介素-6作为结直肠癌术后结直肠吻合口渗漏的早期生物标志物:系统综述和荟萃分析

背景:尽管诊断方法有所进步，但早期发现结直肠吻合口瘘(CAL)仍然具有挑战性。需要可靠的标记物来降低患者的发病率和死亡率。引流液中的细胞因子和全身细胞因子水平已显示出作为CAL预测标志物的潜力，但需要更有力的证据。本系统综述和荟萃分析旨在评估腹膜和血清或血浆白细胞介素-6 (IL-6)水平在结直肠癌患者结直肠癌术后早期检测CAL中的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Surgery, Gastroenterology and Oncology Medicine-Gastroenterology

CiteScore

0.30

自引率

0.00%

发文量

期刊介绍： Starting with this issue "Annals of Fundeni Hospital", founded in 1996 as the scientific journal of the prestigious hospital Fundeni becomes "Journal of Translational Medicine and Research" (JTMR), an Journal of the Academy of Medical Sciences of Romania. Therefore, an 18 years old Journal, attested and indexed in Elsevier Bibliographic Databases, Amsterdam and also indexed in SCOPUS, is continuing a tradition of excellence that lasted almost two decades. The new title of the Journal is inspired first of all from the important developments of translational research In Fundeni Clinical Institute and the "C.C Iliescu Institute for Cardio-Vascular Diseases", in parallel with the national and international trend to promote and develop this important area or medical research. Although devoted mainly to translational research, JTMR will continue to promote both basic and clinical research.