A Critical Study on the Synthetic and Herbal Medication Pattern in the Management of Psoriasis

IF 0.6 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE

Current Traditional Medicine Pub Date : 2023-10-30 DOI:10.2174/0122150838251874231011093514

Shobhini Chandel, Saumya Das, Neha Neha, Vijayant Singh Chauhan

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引用次数: 0

Abstract

Abstract:: Psoriasis is a persistent skin illness that causes dense, shimmering flakes, irritable, dry, and red patches as a result of the fast buildup of skin cells. It is an autoimmune skin condition that is incurable, non-contagious, and relapsing-remitting. Typically, a remission phase lasts one to twelve months. Psoriasis is caused by a number of cellular mechanisms, and it has been hypothesised that T lymphocytes, keratinocytes, allergen cells, Langerhans cells, natural killer cells, phagocytes, a number of Th1-type chemokines, in addition to growth factors like endothelial proliferation factor and keratinocytes growth factor, among others, are key players in the development of psoriasis. Numerous synthetic medicinal drugs have been documented to have the side effects of psoriasis. Due to the safety and accessibility, herbal medications may hold promise as possible anti-psoriatic molecules. Before creating a potential herbal drug, it is important to thoroughly examine the key players in the evolution of psoriasis, such as T-cell stimulation, transportation, and cytokinase inhibition. The purpose of this review is to investigate how psoriasis spreads and becomes activated, as well as how certain medications might exacerbate the condition and how certain plant resources may be used to treat psoriasis. To create a potent, secure, and dependable treatment, more scientific research on these herbal resources is required.

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银屑病综合中药治疗模式的关键研究

摘要:牛皮癣是一种持续的皮肤疾病，由于皮肤细胞的快速积累，导致皮肤出现密集，闪烁的鳞片，易怒，干燥和红色斑块。这是一种自身免疫性皮肤病，无法治愈，非传染性，复发缓解。一般来说，缓解期持续一到十二个月。银屑病是由多种细胞机制引起的，据推测，T淋巴细胞、角质形成细胞、过敏原细胞、朗格汉斯细胞、自然杀伤细胞、吞噬细胞、许多th1型趋化因子，以及内皮细胞增殖因子和角质形成细胞生长因子等生长因子在银屑病的发展中起着关键作用。许多合成药物已被证明有牛皮癣的副作用。由于安全性和可及性，草药可能有望成为抗银屑病分子。在创造一种潜在的草药之前，重要的是要彻底检查牛皮癣演变中的关键因素，如t细胞刺激、运输和细胞激酶抑制。本综述的目的是研究牛皮癣是如何扩散和激活的，以及某些药物是如何加重病情的，以及某些植物资源是如何用于治疗牛皮癣的。为了创造一种有效、安全、可靠的治疗方法，需要对这些草药资源进行更多的科学研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Traditional Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

1.40

自引率

0.00%

发文量

期刊介绍： Current Traditional Medicine covers all the aspects of the modernization and standardization research on traditional medicine of the world, e.g. chemistry, pharmacology, molecular mechanism, systems biology, proteomics, genomics, metabolomics, safety, quality control, clinical studies of traditional Chinese, Ayurvedic, Unani, Arabic and other ethnomedicine. Each issue contains updated comprehensive in-depth/mini reviews along with high quality original experimental research articles. Current Traditional Medicine is a leading and important international peer-reviewed journal reflecting the current outstanding scientific research progresses of the global traditional, indigenous, folk and ethnologic medicine. It provides a bridge connected the tradition medicine system to the modern life science with the efforts of top scientists, as well as a resource to pursuit the solutions for the existing common issues in the traditional medicine.