Association of objectively measured walking speed with incident cardiovascular diseases in middle-aged and older Chinese adults

IF 2.7 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Shuang Peng , Lei Yu , Yuhua Gao , Shan Dong , Yuhui Bai , Guojun Li , Changxue Liang , Zhuoyao Tian , Changsheng Lv , Fu Zhou , Yuan Wei , Ge Wang , Liangming Li , Guang Hao
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引用次数: 0

Abstract

Objective

To evaluate the association between objectively measured walking speed and cardiovascular disease (CVD) risk in middle-aged and elderly Chinese adults.

Methods

A total of 3969 participants from the China Health and Retirement Longitudinal Study (CHARLS) were included in this study. Multilevel logistic and linear regression models (community-household-individual) were used to estimate the association between walking speed and the risk of CVD.

Results

A total of 1037 participants had a CVD event during the follow-up period, including 776 (19.6%) cases of cardiac disease and 353 (8.9%) cases of stroke. Participants who walked faster had a lower risk of CVD (tertile 2: OR = 0.80, 95% CI: 0.67-0.97, P = 0.022; tertile 3: OR = 0.73, 95% CI: 0.60–0.89, P = 0.002). Further analysis showed that participants who walked faster also had a lower risk of cardiac disease and stroke (cardiac disease: tertile 2: OR = 0.91, 95% CI: 0.74–1.12, P = 0.368; tertile 3: OR = 0.85, 95% CI: 0.68–1.07, P = 0.161; stroke: tertile 2: OR = 0.33, 95% CI: 0.14–0.78, P = 0.012; tertile 3: OR = 0.30, 95% CI: 0.11–0.82, P = 0.019). The results were consistent in pre-specified subgroups by sex, age, and body mass index.

Conclusion

We found that faster, objectively measured walking speed was significantly associated with a lower risk of CVD, especially stroke, in middle-aged and elderly Chinese people.

Abstract Image

Abstract Image

客观测量步行速度与中国中老年人心血管疾病发病率的关系
目的:评价中国中老年人客观测量步行速度与心血管疾病(CVD)风险之间的关系。本研究共纳入来自中国健康与退休纵向研究(CHARLS)的3969名参与者。采用多水平logistic和线性回归模型(社区-家庭-个人)来估计步行速度与心血管疾病风险之间的关系。在随访期间,共有1037名参与者发生心血管疾病事件,其中包括776例(19.6%)心脏病病例和353例(8.9%)中风病例。走得快的参与者患心血管疾病的风险较低(Tertile 2: OR=0.80, 95%CI:0.67-0.97, P=0.022;试验3:OR=0.73, 95%CI: 0.60-0.89, P=0.002)。进一步分析表明,走得更快的参与者患心脏病和中风的风险也更低(心脏病:Tertile 2: OR=0.91, 95%CI:0.74-1.12, P=0.368;试验3:OR=0.85, 95%CI: 0.68-1.07, P=0.161;卒中:tile 2: OR=0.33, 95%CI:0.14-0.78, P=0.012;试验3:OR=0.30, 95%CI: 0.11-0.82, P=0.019)。在预先指定的亚组中,性别、年龄和体重指数的结果是一致的。我们发现,在中国中老年人群中,更快的客观测量步行速度与更低的心血管疾病(尤其是中风)风险显著相关。
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来源期刊
Hellenic Journal of Cardiology
Hellenic Journal of Cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
4.90
自引率
7.30%
发文量
86
审稿时长
56 days
期刊介绍: The Hellenic Journal of Cardiology (International Edition, ISSN 1109-9666) is the official journal of the Hellenic Society of Cardiology and aims to publish high-quality articles on all aspects of cardiovascular medicine. A primary goal is to publish in each issue a number of original articles related to clinical and basic research. Many of these will be accompanied by invited editorial comments. Hot topics, such as molecular cardiology, and innovative cardiac imaging and electrophysiological mapping techniques, will appear frequently in the journal in the form of invited expert articles or special reports. The Editorial Committee also attaches great importance to subjects related to continuing medical education, the implementation of guidelines and cost effectiveness in cardiology.
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