Coronary Heart Disease among the Patients of Age between 25-39 and 40-70 Years Attending Cardiology Outdoor of BSMMU, Dhaka, Bangladesh

Md. Hasibul Hasan
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Abstract

Background: Ischemic heart disease (IHD), also known as Coronary Heart Disease (CHD) is a generic designation for a group of related syndromes resulting from myocardial ischemia. It comprises of stable angina, unstable angina, acute myocardial infarction and sudden death. Since the most common cause of IHD is coronary artery abnormality it is also termed as “Coronary artery disease”. Method: This cross sectional observational study was carried out in the department of Cardiology, UCC, BSMMU, Dhaka, during the period of September 2013 to December 2013. A total of 200 patients with primary diagnosis of CHD who were admitted for coronary angiogram were included in this study considering the inclusion and exclusion criteria. Results: Patients aged 25 to 40 years were grouped as group A and a 40 to 70 years were grouped as group B. Baseline clinical history, physical examination and investigations including reports of coronary angiogram were recorded accordingly. There were significant differences between two groups in respect to risk factors and angiographic findings. The prevalence of hypertension and diabetes were found to be more among group B CHD patients compare to group A patient (p<0.001) while, smoking and positive family history of IHD were more prevalent in younger age group (p<0.05). Normal or non-significant CAG findings were more common among group A compared to group B (p<0.05). Multiple vessel disease was observed to be more common amongst group B CHD patients (p<0.01). LAD and RCA involvement was more frequent in group B compared to group A patient (p<0.01). This indicated that risk factors and disease severity was different between two groups. In both the groups male predominance was observed but it was not different between two groups. Other risk factors like obesity and dyslipidemia were not found to be different. Conclusion: Even with best possible effort some limitations have been encountered in this study. Emerging risk factors we discussed .......
25-39岁至40-70岁在孟加拉国达卡BSMMU室外心脏病科就诊的冠心病患者
背景:缺血性心脏病(IHD),又称冠心病(CHD),是由心肌缺血引起的一组相关综合征的总称。它包括稳定型心绞痛、不稳定型心绞痛、急性心肌梗死和猝死。由于IHD最常见的原因是冠状动脉异常,因此也被称为“冠状动脉疾病”。方法:本横断面观察研究于2013年9月至2013年12月在达卡BSMMU UCC心内科进行。根据纳入和排除标准,本研究共纳入200例初步诊断为冠心病并行冠状动脉造影的患者。结果:25 ~ 40岁的患者分为A组,40 ~ 70岁的患者分为b组。记录基线病史、体格检查和包括冠状动脉造影报告的调查。两组在危险因素和血管造影结果方面存在显著差异。B组冠心病患者高血压、糖尿病患病率高于A组(p < 0.001),年轻组吸烟、IHD家族史患病率高于A组(p < 0.05)。与B组相比,A组CAG检查结果正常或不显著的发生率更高(p < 0.05)。多支血管病变在B组冠心病患者中更为常见(p < 0.01)。B组患者LAD和RCA受累频率高于A组(p < 0.01)。这表明两组之间的危险因素和疾病严重程度是不同的。在两组中均观察到男性优势,但两组之间没有差异。其他风险因素,如肥胖和血脂异常,没有发现不同。结论:即使尽了最大的努力,在这项研究中也遇到了一些局限性。我们讨论过的新出现的风险因素.......
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