A fucoidan plant drink reduces Helicobacter pylori load in the stomach: a real-world study

IF 3 4区医学 Q1 Medicine

Translational gastroenterology and hepatology Pub Date : 2023-10-01 DOI:10.21037/tgh-23-63

Qing-Liang Teng, Shu-Jing Sui, Zhen Zhu, Qing Gao, Hui Ge, Ke-Qiang Wang, Leonardo S. Lino-Silva, Michael Sigal, Jonathan R. White, Qi-Hui Peng, You-Zhen Wei

引用次数: 0

Abstract

Background: Helicobacter pylori (Hp) infection is highly prevalent globally and is predominantly managed by antibiotics. Recently, the anti-adhesive, antioxidant, antitoxin, immunomodulatory, anti-coagulant, and anti-infective activities of fucoidan, a polysaccharide extracted from brown seaweeds, have been widely studied, and the results showed promise. Fucoidan has the potential to be utilized in Hp eradication therapy. Our present clinical study was designed to evaluate the efficiency of Lewuyou®, a fucoidan plant drink (FPD) in eradicating Hp in humans.

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岩藻聚糖植物饮料减少胃中幽门螺杆菌的负荷:一项真实世界的研究

背景:幽门螺杆菌(Hp)感染在全球范围内非常普遍，主要通过抗生素治疗。近年来，褐藻多糖的抗黏附、抗氧化、抗毒素、免疫调节、抗凝血和抗感染活性得到了广泛的研究，其研究结果显示出良好的前景。岩藻聚糖有潜力用于Hp根除治疗。我们目前的临床研究旨在评估乐乌游®，一种岩藻聚糖植物饮料(FPD)根除人类Hp的效率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Translational gastroenterology and hepatology Medicine-Gastroenterology

CiteScore

8.20

自引率

0.00%

发文量

期刊介绍： Translational Gastroenterology and Hepatology (Transl Gastroenterol Hepatol; TGH; Online ISSN 2415-1289) is an open-access, peer-reviewed online journal that focuses on cutting-edge findings in the field of translational research in gastroenterology and hepatology and provides current and practical information on diagnosis, prevention and clinical investigations of gastrointestinal, pancreas, gallbladder and hepatic diseases. Specific areas of interest include, but not limited to, multimodality therapy, biomarkers, imaging, biology, pathology, and technical advances related to gastrointestinal and hepatic diseases. Contributions pertinent to gastroenterology and hepatology are also included from related fields such as nutrition, surgery, public health, human genetics, basic sciences, education, sociology, and nursing.

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