Karen S. Andrade , Antonio V. Diniz Merladet , Thomas M. Klapötke , Chiara Manfletti
{"title":"Safety improvements for laboratory handling of energetic materials applying system-theoretic process analysis","authors":"Karen S. Andrade , Antonio V. Diniz Merladet , Thomas M. Klapötke , Chiara Manfletti","doi":"10.1016/j.jsse.2023.10.005","DOIUrl":null,"url":null,"abstract":"<div><p><span>Over the past few years, numerous accidents have occurred during dangerous chemical experiments. Although there is a considerable amount of literature on laboratory safety, there is still a lack of systematic research that examines how the various laboratory systems interact and potentially contribute to accidents. The objective of this work is to lessen </span>accidents and incidents<span> related to Handling Energetic Materials in Research Laboratories by utilizing STPA (System-Theoretic Process Analysis). This involves examining unsafe interactions between system components, detecting potential undesired events, and implementing measures to prevent or reduce their impact. Recent literature on laboratory safety, quality standards, and interviews with lab workers were used as data sources for the STPA elaboration. As a result, it was possible to identify Unsafe Control Actions, Loss Scenarios, Causal Factors, and Safety Constraints to be considered to avoid undesired events or to mitigate their consequences during the Energetic Material Handling in research centers. It was also possible to point out key measures that can reduce waste, enhance productivity, allocate resources more effectively, decrease accidents, and, most importantly, mitigate potential hazards in laboratory work. The SPTA analysis presented a way to improve laboratory safety management and ensure a safer and more productive research environment.</span></p></div>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2468896723001027","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Over the past few years, numerous accidents have occurred during dangerous chemical experiments. Although there is a considerable amount of literature on laboratory safety, there is still a lack of systematic research that examines how the various laboratory systems interact and potentially contribute to accidents. The objective of this work is to lessen accidents and incidents related to Handling Energetic Materials in Research Laboratories by utilizing STPA (System-Theoretic Process Analysis). This involves examining unsafe interactions between system components, detecting potential undesired events, and implementing measures to prevent or reduce their impact. Recent literature on laboratory safety, quality standards, and interviews with lab workers were used as data sources for the STPA elaboration. As a result, it was possible to identify Unsafe Control Actions, Loss Scenarios, Causal Factors, and Safety Constraints to be considered to avoid undesired events or to mitigate their consequences during the Energetic Material Handling in research centers. It was also possible to point out key measures that can reduce waste, enhance productivity, allocate resources more effectively, decrease accidents, and, most importantly, mitigate potential hazards in laboratory work. The SPTA analysis presented a way to improve laboratory safety management and ensure a safer and more productive research environment.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.