Thiazide diuretics in chronic kidney disease: Is there still a role?

IF 5.2 4区 医学 Q2 Medicine
Sabrina Haroon, Matthew Edward Cove
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引用次数: 0

Abstract

Hypertension is both a cause and consequence of chronic kidney disease (CKD). As such, the prevalence of hypertension is high among CKD patients and the incidence increases as their kidney disease progresses. Given the high risk of mortality, morbidity and risk of progression to end-stage renal failure, blood pressure management remains a key focus in managing CKD patients. However, without strong definitive evidence for blood pressure targets, or clear data to support the precise combination of antihypertensive medications, practice variance increases as the number of drugs available to treat hypertension increases and older drug classes may be overlooked.
噻嗪类利尿剂在慢性肾病中的作用?
高血压是慢性肾脏疾病(CKD)的原因和结果。因此,CKD患者中高血压的患病率很高,并且随着肾脏疾病的进展,其发病率也会增加。鉴于死亡率、发病率和进展为终末期肾衰竭的高风险,血压管理仍然是CKD患者管理的关键焦点。然而,如果没有关于血压目标的强有力的明确证据,或者没有明确的数据来支持抗高血压药物的精确组合,实践差异就会随着治疗高血压的药物数量的增加而增加,而老的药物类别可能会被忽视。
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来源期刊
Annals Academy of Medicine Singapore
Annals Academy of Medicine Singapore 医学-医学:内科
CiteScore
4.90
自引率
5.80%
发文量
186
审稿时长
6-12 weeks
期刊介绍: The Annals is the official journal of the Academy of Medicine, Singapore. Established in 1972, Annals is the leading medical journal in Singapore which aims to publish novel findings from clinical research as well as medical practices that can benefit the medical community.
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