Amit Ghosh , Soham Ghosh , Falguni Pati , Suhanya Duraiswamy
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引用次数: 0
Abstract
Cancer cells do not exist in isolation; their dynamic interaction with other cells and non-cell components in the tumor microenvironment (TME) allows them to divide and evolve. Recent research has significantly impacted the importance of TME in vitro models for cancer therapy and the varied degrees of complexity among them. The complex biology of the TME has been recreated using cutting-edge technologies, including 3D bioprinting and tumor-on-a-chip models using different cell types and biomaterials. Therefore, it is crucial to classify the recently produced 3D in-vitro cancer models according to the cell type population(s) used to mimic the complexity. By concentrating on the relevance of these models to in-vivo conditions, this review attempts to strengthen the foundation for chemotherapeutic drug research and personalized treatment.
期刊介绍：
Bioprinting is a broad-spectrum, multidisciplinary journal that covers all aspects of 3D fabrication technology involving biological tissues, organs and cells for medical and biotechnology applications. Topics covered include nanomaterials, biomaterials, scaffolds, 3D printing technology, imaging and CAD/CAM software and hardware, post-printing bioreactor maturation, cell and biological factor patterning, biofabrication, tissue engineering and other applications of 3D bioprinting technology. Bioprinting publishes research reports describing novel results with high clinical significance in all areas of 3D bioprinting research. Bioprinting issues contain a wide variety of review and analysis articles covering topics relevant to 3D bioprinting ranging from basic biological, material and technical advances to pre-clinical and clinical applications of 3D bioprinting.
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