In vitro antimicrobial activity of Brassica nigra , Trigonella foenum-graecum , and Schinus molle in Ethiopia against selected human bacterial pathogens
{"title":"In vitro antimicrobial activity of <i>Brassica nigra</i> , <i>Trigonella foenum-graecum</i> , and <i>Schinus molle</i> in Ethiopia against selected human bacterial pathogens","authors":"Addisu Assefa, Helmut Kloos, Assegid Zewdu","doi":"10.1080/10496475.2023.2269372","DOIUrl":null,"url":null,"abstract":"ABSTRACTAntimicrobial activity of solvent extracts of Brassica nigra, Trigonella foenum-graecum, and Schinus molle were investigated against six bacterial pathogens. The highest zone of inhibition (ZOI) were noted for methanol extract of B. nigra against S. boydii. The highest activity index (AI) was noted in methanol extract of B. nigra against S. boydi (AI = 0.86) using ciprofloxacin as positive control but AI ≥ 1.0 in some extracts while using gentamicin as positive control. The minimum inhibitory concentration (MIC) of the extracts ranged from 6.25 mg mL−1 to 100 mg mL−1. The antibacterial activity of the extracts was B. nigra > T. foenum-graecum > S. molle.KEYWORDS: Antibacterial activityactivity indextest bacterial pathogens AcknowledgmentsWe thank the Department of Biology, the College of Natural and Computational Sciences, and the School of Graduate Studies of Madda Walabu University for their administrative and material support. We are also highly grateful to the Ethiopian Public Health Institute for providing us the bacterial test pathogens used in this study. The National Herbarium in Addis Ababa (Ethiopia) is also acknowledged for its cooperation in the identification of plant samples used in this study. We also thank Ann Byers for editing the manuscript at short notice.Disclosure statementNo potential conflict of interest was reported by the author(s).Data availability statementAll relevant data are within the manuscript and its supporting information files.Supplementary materialSupplemental data for this article can be accessed online at https://doi.org/10.1080/10496475.2023.2269372Additional informationFundingThe authors received no specific funding from any sources.","PeriodicalId":35803,"journal":{"name":"Journal of Herbs, Spices and Medicinal Plants","volume":null,"pages":null},"PeriodicalIF":1.2000,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Herbs, Spices and Medicinal Plants","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/10496475.2023.2269372","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
Abstract
ABSTRACTAntimicrobial activity of solvent extracts of Brassica nigra, Trigonella foenum-graecum, and Schinus molle were investigated against six bacterial pathogens. The highest zone of inhibition (ZOI) were noted for methanol extract of B. nigra against S. boydii. The highest activity index (AI) was noted in methanol extract of B. nigra against S. boydi (AI = 0.86) using ciprofloxacin as positive control but AI ≥ 1.0 in some extracts while using gentamicin as positive control. The minimum inhibitory concentration (MIC) of the extracts ranged from 6.25 mg mL−1 to 100 mg mL−1. The antibacterial activity of the extracts was B. nigra > T. foenum-graecum > S. molle.KEYWORDS: Antibacterial activityactivity indextest bacterial pathogens AcknowledgmentsWe thank the Department of Biology, the College of Natural and Computational Sciences, and the School of Graduate Studies of Madda Walabu University for their administrative and material support. We are also highly grateful to the Ethiopian Public Health Institute for providing us the bacterial test pathogens used in this study. The National Herbarium in Addis Ababa (Ethiopia) is also acknowledged for its cooperation in the identification of plant samples used in this study. We also thank Ann Byers for editing the manuscript at short notice.Disclosure statementNo potential conflict of interest was reported by the author(s).Data availability statementAll relevant data are within the manuscript and its supporting information files.Supplementary materialSupplemental data for this article can be accessed online at https://doi.org/10.1080/10496475.2023.2269372Additional informationFundingThe authors received no specific funding from any sources.
期刊介绍:
The Journal of Herbs, Spices & Medicinal Plants is an essential reference filled with recent research and other valuable information associated with herbs, spices, and medicinal plants. The Journal serves as a focus point through which investigators and others may publish material of importance to the production, marketing, and utilization of these plants and associated extracts. The journal covers the following topics: growth, development, horticulture, ecology, physiology, genetics, chemistry, and economics. Original articles, review articles, and book reviews provide information of interest to an international audience of researchers, teachers, technicians, and managers involved with production and/or marketing of herbs, spices, and medicinal plants. Managers of food companies, food processing facilities, medical research laboratories, government agencies, and others interested in new chemicals, food additives, international trade, patents, and other items can easily review new findings. The Journal of Herbs, Spices & Medicinal Plants is a forum in which recent research and other information associated with herbs, spices, and medicinal plants is shared. The Journal represents a centralized database accessible by investigators within the international community that work with or have an interest in herbs, spices, and medicinal plants.