Clinical Parameters in the First 5 Minutes after Birth Have a Predictive Value for Survival of Extremely Preterm Infants

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-10-01 DOI:10.1097/fm9.0000000000000206

Laura Torrejón-Rodríguez, Álvaro Solaz-García, Inmaculada Lara-Cantón, Alejandro Pinilla-González, Marta Aguar, Máximo Vento

引用次数: 0

Abstract

Abstract Extreme preterm infants (<28 weeks' gestation) often require positive pressure ventilation with oxygen during postnatal stabilization in the delivery room. To date, optimal inspired fraction of oxygen (FiO 2 ) still represents a conundrum in newborn care oscillating between higher (>60%) and lower (<30%) initial FiO 2 . Recent evidence and meta-analyses have underscored the predictive value for survival and/or relevant clinical outcomes of the Apgar score and the achievement of arterial oxygen saturation measured by pulse oximetry ≥85% at 5 minutes after birth. New clinical trials comparing higher versus lower initial FiO 2 have been launched aiming to optimize postnatal stabilization of extreme preterm while avoiding adverse effects of hypoxemia or hyperoxemia.

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出生后5分钟的临床参数对极早产儿的生存具有预测价值

摘要极端早产儿(妊娠28周)在产房产后稳定期间经常需要正压通气加氧气。迄今为止，最佳吸入氧分数(FiO 2)仍然是新生儿护理中的一个难题，在较高(60%)和较低(30%)的初始FiO 2之间摇摆。最近的证据和荟萃分析强调了Apgar评分和出生后5分钟动脉血氧饱和度≥85%对生存和/或相关临床结果的预测价值。新的临床试验已经启动，旨在比较较高和较低的初始FiO 2，以优化极端早产儿的产后稳定，同时避免低氧血症或高氧血症的不良影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.