Home Monitoring for Fever: An Inexpensive Screening Method to Prevent Household Spread of COVID-19

Justin Kim, Marcus A Threadcraft, Wei Xue, Sijie Yue, Richard P Wenzel, Frederick S Southwick
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Abstract

The COVID-19 pandemic surge has exceeded testing capacities in many parts of the world. We investigated the effectiveness of home temperature monitoring for early identification of COVID-19 patients. Study Design: We compared home temperature measurements from a convenience sample of 1180 individuals who reported being test positive for SARS-CoV-2 to an age, sex, and location matched control group of 1249 individuals who had not tested positive. Methods: All individuals monitored their temperature at home using an electronic smartphone thermometer that relayed temperature measurements and symptoms to a centralized cloud based, de-identified data bank. Results: Individuals varied in the number of times they monitored their temperature. When temperature was monitored for over 72 hours fever (> 37.6°C or 99.7°F or a change in temperature of > 1°C or 1.8°F) was detected in 73% of test positive individuals, a sensitivity comparable to rapid SARS-CoV-2 antigen tests. When compared our control group the specificity of fever for COVID-19 was 0.70. However, when fever was combined with complaints of loss of taste and smell, difficulty breathing, fatigue, chills, diarrhea, or stuffy nose the odds ratio of having COVID-19 was sufficiently high as to obviate the need to employ RTPCR or antigen testing to screen for and isolate coronavirus infected cases. Conclusions: Our findings suggest that home temperature monitoring could serve as an inexpensive convenient screen for the onset of COVID-19, encourage earlier isolation of potentially infected individuals, and more effectively reduce the spread of infection in closed spaces.
家庭发热监测:预防COVID-19家庭传播的一种廉价筛查方法
在世界许多地方,COVID-19大流行的激增超出了检测能力。探讨家庭温度监测对早期发现COVID-19患者的有效性。研究设计:我们将来自1180名报告SARS-CoV-2检测呈阳性的方便样本的家庭温度测量值与年龄、性别和位置匹配的1249名未检测呈阳性的对照组进行了比较。方法:所有个体在家中使用电子智能手机体温计监测体温,该体温计将温度测量值和症状转发到基于云的集中式去识别数据库。结果:个体监测体温的次数各不相同。当监测温度超过72小时时,73%的检测阳性个体检测到发热(> 37.6°C或99.7°F或温度变化> 1°C或1.8°F),其敏感性与快速SARS-CoV-2抗原检测相当。与对照组相比,发热对COVID-19的特异性为0.70。然而,当发烧并伴随着味觉和嗅觉丧失、呼吸困难、疲劳、发冷、腹泻或鼻塞的抱怨时,感染COVID-19的优势比足够高,以至于不需要使用RTPCR或抗原检测来筛查和分离冠状病毒感染病例。结论:我们的研究结果表明,家庭温度监测可以作为COVID-19发病的廉价便捷筛查,鼓励早期隔离潜在感染者,并更有效地减少感染在封闭空间的传播。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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