Study of the Role of Vitamin (D) Deficiency in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Mohamed Yahia Mohamed Morsi, Ibrahim Mahmoud Shalan, Wageeh Hassan Sayed
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Abstract

Background; COPD is a variety of lung symptoms that are characterized by persistent, frequently worsening airflow restriction and chronic respiratory symptoms (dyspnea, cough, and formation of sputum) owing to diseases in the bronchial tree (bronchiolitis, bronchitis), or/and alveoli (emphysema), objectives; to research the impact of vitamin (D) deficiency in individuals with stable and acute exacerbation COPD, Subjects and methods; This case control study was carried out at Al- Azhar University Hospital-Assuit between February 2022 and December 2022 on (100) COPD patients and another (50) control group of individuals who looked to be in good health. Result; Moreover, Levels of vitamin (D) were markedly high in controls compared to Stable COPD group and levels of vitamin D were relatively high in Stable COPD compared to AECOPD group, Conclusion; AECOPD patients were shown to have vitamin D insufficiency and vitamin D insufficiency was strongly related to severity of COPD. Vitamin D insufficiency was also related to illness exacerbation.
慢性阻塞性肺疾病急性加重期维生素D缺乏的研究
背景;慢性阻塞性肺病是一种肺部症状,其特征是持续的、经常恶化的气流受限和慢性呼吸道症状(呼吸困难、咳嗽和痰),这是由支气管树疾病(细支气管炎、支气管炎)或/和肺泡(肺气肿)引起的。研究维生素D缺乏对稳定期和急性加重期COPD患者的影响,研究对象和方法;这项病例对照研究于2022年2月至2022年12月在爱资哈尔大学附属医院进行,研究对象为(100)名COPD患者和另一组(50)名健康状况良好的对照组个体。结果;此外,与AECOPD组相比,对照组的维生素D水平明显较高,而稳定型COPD组的维生素D水平相对较高。AECOPD患者存在维生素D不足,维生素D不足与COPD的严重程度密切相关。维生素D不足也与疾病恶化有关。
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