Dextranomer/Hyalouronic Acid Copolymer Injection for Treatment of Children with Primary Vesicoureteral Reflux: Long-Term Follow-up

Osama M Ahmed, Hany A El-Damanhory, Esayed M Salih
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Abstract

Purpose: We aim to present our 5 years results with Dextranomer/Hyalouronic Acid (Dx/HA) sub-ureteral injection for treatment of children with primary vesico ureteric reflux (VUR). PATIENTS AND METHODS: The retrospective cohort study which was performed at tertiary referral center in Cairo. Children underwent Dx/HA injection for treatment of the primary VUR were reviewed. Only those he had full medical record dating 5 years or earlier included into the study. Results: Sixty patients, 25 boys and 35 girls in total 82 ureters had refluxed underwent DX/HA injections. The patients' average age was 5.70 years. Eight (9.7%) of the 82 ureters that were treated failed all three injections, leaving 74 (90.3%) of them completely cured. Conclusion: This acceptable improvement sustainability of the DX/HA sub-uretral injection in children with 1ry VUR highlights the benefits of this procedures. The minimally invasive nature, the short hospital stay are definite advantages.
葡聚糖/透明质酸共聚物注射治疗儿童原发性膀胱输尿管反流:长期随访
目的:我们的目标是展示我们5年来右旋聚体/透明质酸(Dx/HA)输尿管下注射治疗原发性膀胱输尿管反流(VUR)儿童的结果。患者和方法:回顾性队列研究在开罗三级转诊中心进行。我们回顾了接受Dx/HA注射治疗原发性VUR的儿童。只有那些5年或更早有完整医疗记录的人被纳入研究。结果:60例患者(男25例,女35例)共82条输尿管返流,行DX/HA注射。患者平均年龄5.70岁。治疗的82条输尿管中有8条(9.7%)输尿管三次注射均失败,74条(90.3%)输尿管完全治愈。结论:DX/HA输尿管下注射在1ry VUR患儿中可接受的改善可持续性突出了该手术的益处。微创性强,住院时间短,具有明显的优势。
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