Interplay between Lipid Profile and Weight-Related Outcomes in Healthy Overweight Adults: In-sights from Comprehensive Analyses

Louis O. Odeigah, Olalekan A. Agede, Sunday B. Ogunjemilua, Ismaila A. Obalowu, Yahkub B. Mutalub
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Abstract

Background: The escalating prevalence of overweight and obesity has heightened concerns about cardiovascular health. The intricate interplay between lipid profile variables and weight-related outcomes plays a pivotal role in shaping cardiovascular risks among individuals with excess body weight. This study investigates the associations between lipid profile variables and weight-related indicators in a cohort of healthy, overweight adults, shedding light on potential implications for cardiovascular risk management. Methods: The prevalence of metabolic syndrome, risk factors, and related lifestyle in adult Myanmar citizens were examined in the Inter-University Consortium for Political and Social Research Study (ICPSR146521) using prospective data. The patient’s lipid profiles and demographic data were statistically analyzed using the statistical MedCalc tool. Statistical significance was determined using a 0.05 p-value. Results: Results demonstrate that while BMI is influenced by multiple factors beyond lipid profile variables, waist circumference exhibits moderate association with these variables. Notably, triglycerides significantly correlated with waist circumference, suggesting a potential role in visceral fat accumulation. Additionally, the study highlights the impact of high-density lipoprotein (HDL) cholesterol levels on body weight, indicating that higher HDL levels are associated with lower body weights among healthy overweight adults. Conclusion: This study provides comprehensive insights into the complex relationship between lipid profile variables and weight-related outcomes among healthy, overweight adults. These findings underscore the importance of weight management strategies for cardiovascular health and suggest potential avenues for targeted interventions. By understanding the interplay between lipid profiles and obesity, clinicians and public health professionals can develop more effective strategies to mitigate cardiovascular risks in this demographic
健康超重成人的脂质特征与体重相关结果之间的相互作用:来自综合分析的见解
背景:超重和肥胖的日益流行加剧了人们对心血管健康的关注。脂质谱变量和体重相关结果之间复杂的相互作用在塑造超重个体的心血管风险中起着关键作用。本研究调查了健康超重成人队列中脂质谱变量与体重相关指标之间的关系,揭示了心血管风险管理的潜在意义。方法:在大学间政治和社会研究联盟(ICPSR146521)中使用前瞻性数据调查缅甸成年公民代谢综合征的患病率、危险因素和相关生活方式。使用统计MedCalc工具对患者的血脂和人口统计学数据进行统计分析。采用0.05 p值确定统计学显著性。结果:结果表明,虽然BMI受血脂变量以外的多种因素的影响,但腰围与这些变量表现出适度的关联。值得注意的是,甘油三酯与腰围显著相关,表明其在内脏脂肪积累中的潜在作用。此外,该研究强调了高密度脂蛋白(HDL)胆固醇水平对体重的影响,表明在健康超重的成年人中,较高的HDL水平与较低的体重有关。结论:本研究为健康超重成人的脂质谱变量与体重相关结果之间的复杂关系提供了全面的见解。这些发现强调了体重管理策略对心血管健康的重要性,并提出了有针对性干预的潜在途径。通过了解脂质谱和肥胖之间的相互作用,临床医生和公共卫生专业人员可以制定更有效的策略来降低这一人群的心血管风险
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