Isolation and Characterization of Phytoconstituents from the Plant Excoecaria agallocha Linn

Q4 Pharmacology, Toxicology and Pharmaceutics
Maruti K Shelar, Manohar J Patil, Santosh S Patil
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引用次数: 0

Abstract

Background: Marine resources are currently widely studied because academic and industrial researchers are striving to extract lead molecules from the interior of oceans. Marine resources are increasingly the subject of significant research. Excoecaria agallocha Linn., one of the plants with several pharmacological effects such as anti-inflammatory, analgesic, antiulcer, anticancer, etc., is one of the phytoconstituents in mangroves that have been widely used in folk medicine to treat disorders. Objective: The objective of present study to perform a comprehensive phytochemical investigation of milky mangrove. The plant E. agallocha were collected, extracted, isolated, and analyzed in an attempt to better comprehend the various phytochemical aspects of the plant. Material and method: The isolated product was analyzed by different spectroscopic method. Results: The isolated product is characterized as steroidal moiety containing two double bond at 6 and 22-position and alcoholic group at 3-position of cyclopentanoperhydrophenanthrene in to the isolation of (1,2,3,4,5,10,11,12,14,15,17-dodecahydro-3-hydroxy-4,4,10,13,14-pentamethyl17-(( E )- 5,6-dimethylhept-3-en- 2- yl-)9-H-cyclopenta[a]phenanthren-6,16-dione. Conclusion: The compound’s actual structure is made known using all of the UV, IR, NMR, and mass spectrometry evidence
沉香果属植物成分的分离与鉴定
背景:海洋资源目前被广泛研究,因为学术界和工业界的研究人员正在努力从海洋内部提取铅分子。海洋资源日益成为重要的研究课题。香椿芽;红树是具有抗炎、镇痛、抗溃疡、抗癌等药理作用的植物之一,是红树中被广泛用于民间医学治疗疾病的植物成分之一。目的:对乳红树进行全面的植物化学研究。为了更好地了解该植物的各种植物化学方面,我们收集、提取、分离和分析了该植物。材料与方法:采用不同的光谱方法对分离产物进行分析。结果:分离产物为环戊过氢菲6、22位含两个双键和3位含醇基团的甾体片段,分离得到(1,2,3,4,5,10,11,12,14,15,17-十二氢-3-羟基-4,4,10,13,14-五甲基17-((E)- 5,6-二甲基庚-3-烯- 2-基-)9- h -环戊[a]菲6,16-二酮。结论:化合物的实际结构是已知的使用所有的紫外,红外,核磁共振和质谱的证据
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来源期刊
International Journal of Drug Delivery Technology
International Journal of Drug Delivery Technology Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
0.70
自引率
0.00%
发文量
0
期刊介绍: International Journal of Drug Delivery Technology (IJDDT) provides the forum for reporting innovations, production methods, technologies, initiatives and the application of scientific knowledge to the aspects of pharmaceutics, including controlled drug release systems, drug targeting etc. in the form of expert forums, reviews, full research papers, and short communications.
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