Assessment of Blood Lipids in People with Chronic Hypertensive

Q4 Pharmacology, Toxicology and Pharmaceutics
Methaq N Mahmood, Noor S Hasan, Sabreen H Majeed
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引用次数: 0

Abstract

High blood pressure remains one of the world’s leading health problems. High blood pressure is already manageable, and early detection can prevent complications by using therapy or changing lifestyle to healthy habits. High blood pressure and dyslipidemia are two of the main hazard factors for cardiovascular disease. The current study was conducted on 60 male and female samples aged 35 to 70 years, which divided the samples into three groups each group including 20 samples. The first group are healthy people who don’t have high blood pressure or chronic diseases (control group), the second group of patients with chronic hypertension without treatment but follow lifestyle modification, and the third group of patients with chronic hypertension with treatment the active substance hydrochlorothiazide and Losartan potassium, The regulated questionnaire information was recorded for all members of the sample and was measured the lipid profile test of triglycerides, cholesterol, lipoprotein (HDL, VLDL, LDL) in serum, atherogenic index plasma, body mass index (BMI), waistline. Levels of triglycerides and cholesterol were a non-significant increase in group of patients hypertensive without treatment and a significant increase in group of patients hypertensive with treatment than the control group. The results of lipoproteins showed non-significant differences than the control group while there was a significant increase in the VLDL level of group patients hypertensive with treatment than the control group. The results also indicated non-significant differences in the groups of atherogenic index plasma, body mass index and waistline measurement except for group of patients hypertensive without treatment that showed a significant increase in BMI than control group.
慢性高血压患者血脂的评估
高血压仍然是世界上主要的健康问题之一。高血压已经是可以控制的,早期发现可以通过治疗或改变健康的生活习惯来预防并发症。高血压和血脂异常是心血管疾病的两个主要危险因素。本次研究选取了年龄在35岁到70岁之间的60名男性和女性样本,将样本分为三组,每组20个样本。第一组为无高血压或慢性病的健康人群(对照组),第二组为未接受治疗但改变生活方式的慢性高血压患者,第三组为接受活性物质氢氯噻嗪和氯沙坦钾治疗的慢性高血压患者,记录所有样本成员的规范问卷信息,并测量甘油三酯脂质谱测试。胆固醇,血清脂蛋白(HDL, VLDL, LDL),血浆动脉粥样硬化指数,体重指数(BMI),腰围。与对照组相比,未接受治疗的高血压患者的甘油三酯和胆固醇水平无显著升高,接受治疗的高血压患者的甘油三酯和胆固醇水平有显著升高。与对照组相比,治疗组患者的脂蛋白水平差异无统计学意义,而治疗组患者的VLDL水平明显高于对照组。结果还表明,除了未经治疗的高血压患者组BMI明显高于对照组外,各组之间的动脉粥样硬化指数、血浆、体重指数和腰围测量均无显著差异。
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来源期刊
International Journal of Drug Delivery Technology
International Journal of Drug Delivery Technology Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
0.70
自引率
0.00%
发文量
0
期刊介绍: International Journal of Drug Delivery Technology (IJDDT) provides the forum for reporting innovations, production methods, technologies, initiatives and the application of scientific knowledge to the aspects of pharmaceutics, including controlled drug release systems, drug targeting etc. in the form of expert forums, reviews, full research papers, and short communications.
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