Drug-drug interactions of immunosuppressants and other drugs in kidney post-transplant recipients

Mariel Umana-Rivas, Evelin Soares de Brito, Letícia Santana da Silva Soares, Geraldo Rubens Ramos de Freitas, Gustavo Queiroz Arimatea, Priscila Dias Gonçalves, Dayani Galato
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Abstract

Immunosuppressants (ISS) are the most crucial tools used in the therapeutic regimens of transplant recipients. Nevertheless, these drugs are not the only ones adopted by patients; therefore, knowing the possible drug-drug interactions (DDIs) between immunosuppressants and other drugs commonly used in kidney transplant recipients is essential to ensure the effectiveness and safety of treatments. In this way, the objective is analyzing the DDIs between the immunosuppressants and other commonly used medications on kidney transplant adult recipients with active medical records undergoing post-transplant follow-up for 4.4 years (mean).
肾移植后受者免疫抑制剂和其他药物的药物相互作用
免疫抑制剂(ISS)是移植受者治疗方案中最重要的工具。然而,这些药物并不是患者采用的唯一药物;因此,了解免疫抑制剂与肾移植受者常用的其他药物之间可能的药物-药物相互作用(ddi)对于确保治疗的有效性和安全性至关重要。通过这种方式,目的是分析免疫抑制剂和其他常用药物在肾移植后随访4.4年(平均)的积极医疗记录的成人肾移植受者的ddi。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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