Comparing the effects of injecting bupivacaine, tramadol, and bupivacaine-tramadol combination at the surgical incision site on pain intensity and postoperative complications in patients undergoing elective cesarean section: A randomized controlled trial

Abstract

Background

cesarean sections (C-sections) are the most popular surgical procedure for women of reproductive age. In the majority of procedures, effective postoperative pain management is crucial for postoperative care in order to lower morbidity and mortality while also making patients feel comfortable. The current study aims to compare the effects of injecting bupivacaine, tramadol, and bupivacaine-tramadol combination at the surgical incision site in patients undergoing elective cesarean section.

Method

The current study is a double-blind randomized clinical trial that included patients September of pregnant women referred to Obstetrics and Gynecology Clinic between 2021 June and 2022 September.

Results

This study included 180 patients (60 in each group). The average age of the patients was 31.33 years, and the difference in vas 6, vas 12, and vas 24 scores between groups was significant (P > 0.001). The group that used drugs in combination experienced significantly less pain and there was no significant difference in analgesic drug consumption.

Discussion and conclusion

results of the current study revealed there was a significant difference in vas 6, vas 12, and vas 24 scores between the groups, with the group of bupivacaine-tramadol combination providing a greater analgesic effect. However, there is no statistically significant difference in the frequency of post-operative side effects.