Remarkable Breakthrough: Unleashing the Power of Paclitaxel and Carboplatin in Defeating Squamous Cell Carcinoma (SCC) of the Lungs - A Compelling Case Report

Novita Andayani, Murtaza Murtaza, Rina Marlena, Syarifah Fera Muhawan
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Abstract

Background: This case report focuses on the evaluation of treatment efficacy in a 64-year-old male patient diagnosed with stage IVA lung squamous cell carcinoma (SCC) in the right upper lobe. The patient underwent chemotherapy using paclitaxel and carboplatin, administered in measured doses over six cycles. Close monitoring of patients was conducted throughout the treatment period, taking into account their clinical condition. Case: The patient underwent a computerized tomography (CT) examination before starting treatment, followed by a comparison in the third month of treatment. Encouragingly, significant clinical improvement was observed with respect to the initial complaint. The patient achieved an excellent response, the tumor appearance disappeared and the previous size was assessed by Partial Response (PR) based on RECIST criteria. Discussions: The administration of paclitaxel and carboplatin in patients with SCC gave positive results. Metered doses and scheduled administration allow for effective disease management, leading to substantial clinical improvement. The case studies highlight the potential of this treatment regimen in treating SCC, emphasizing the importance of close monitoring during therapy. Conclusion: This case report underscores the promising results obtained with paclitaxel and carboplatin in the treatment of lung SCC. The patient's notable response, marked by clinical improvement and achieving a partial response based on RECIST criteria, exemplifies the potential of this therapeutic approach. Further investigations and clinical trials are warranted to explore the broader applicability and efficacy of this regimen.
显著突破:释放紫杉醇和卡铂治疗肺部鳞状细胞癌(SCC)的力量——一个令人信服的病例报告
背景:本病例报告主要评价一例64岁男性右上叶IVA期肺鳞状细胞癌(SCC)的治疗效果。患者接受了紫杉醇和卡铂的化疗,在六个周期内给予测量剂量。考虑到患者的临床状况,在整个治疗期间对患者进行了密切监测。病例:患者在开始治疗前进行了计算机断层扫描(CT)检查,随后在治疗的第三个月进行了比较。令人鼓舞的是,与最初的抱怨相比,观察到显著的临床改善。患者获得了良好的反应,肿瘤外观消失,根据RECIST标准通过部分缓解(PR)评估先前的大小。讨论:紫杉醇和卡铂在SCC患者中的应用取得了积极的结果。计量剂量和计划给药允许有效的疾病管理,导致实质性的临床改善。这些病例研究强调了这种治疗方案在治疗SCC方面的潜力,强调了在治疗期间密切监测的重要性。结论:本病例报告强调了紫杉醇联合卡铂治疗肺鳞状细胞癌的良好结果。根据RECIST标准,该患者的显著反应表现为临床改善和部分缓解,证明了这种治疗方法的潜力。进一步的调查和临床试验是必要的,以探索更广泛的适用性和有效性的方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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