Synthesis and Characterization of a Polymeric Material Blended to Bone Forming Elements

Esther Perez-Torrero, Leticia Esmeralda Luna-Rodriguez, Gerardo Antonio Fonseca-Hernandez, Jose Santos-Cruz, Eric Mauricio Rivera-Muñoz, Maria Lucero Gomez-Herrera
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Abstract

A synthetizing material blended with two distinct proteins (collagen and casein) and mineral mixture, was developed in order to evaluate their properties suitable for possible applications in the biomedical such as inducing the regeneration of damaged bone, either due to an accident or illness. Samples were evaluated by 1) Mechanical properties tests under the bending, 2) Scanning electronic microscopy and 3) Infrared spectroscopy were carried out. The results showed that the developed material has breaking strength and structure characteristics associated with the protein used in their composition. This fact suggests that the used protein determines the resistance of the material, in such a way according to the required use, being able to choose appropriate strength and duration either short or long time. The material composition for specific use, in order to find the most suitable mixture for bone replacement, or induce bone recovery, according to the required properties similar to those of damaged living tissue.
复合骨形成材料的合成与表征
一种由两种不同的蛋白质(胶原蛋白和酪蛋白)和矿物质混合物混合而成的合成材料被开发出来,以评估其性能是否适合在生物医学领域的可能应用,例如诱导因事故或疾病而受损的骨骼再生。通过1)弯曲力学性能测试,2)扫描电镜和3)红外光谱对样品进行了表征。结果表明,所开发的材料具有断裂强度和结构特征,与所使用的蛋白质有关。这一事实表明,所使用的蛋白质决定了材料的抵抗力,以这种方式根据所需的用途,能够选择适当的强度和持续时间,无论是短的还是长的。针对特定用途的材料组合物,为了找到最合适的混合物进行骨置换,或诱导骨恢复,根据所需要的类似于受损活组织的特性。
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