Drying curve simulation and LF-NMR online monitor of water state in ursolic acid loaded chitosan nanoparticles during microwave freeze drying

IF 2.2 2区农林科学 Q2 AGRICULTURAL ENGINEERING

International Journal of Agricultural and Biological Engineering Pub Date : 2023-01-01 DOI:10.25165/j.ijabe.20231604.7519

Xing Ren, Xu Duan, Weiwei Cao, Lujie Zhao, Guangyue Ren, Panpan Liu

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引用次数: 0

Abstract

Changes in various states of water in ursolic acid (UA) loaded chitosan nanoparticles were assessed using low-field nuclear magnetic resonance (LF-NMR) during microwave freeze drying (MFD) process, and six thin-layer models were applied to simulate the drying kinetics. UA nanoparticles were dried at different microwave power densities (1 W/g, 2 W/g and 4 W/g). The results showed that three water fractions with different transverse relaxation times (T2) were detected in fresh UA nanoparticles. The T2 relaxation time of water decreased significantly with the increase of drying time at different microwave power densities. And the mutual migration and transformation of water in different states during the drying process of chitosan nanoparticles occurred. Furthermore, mathematical model analysis showed that the Page model provided the best description during the process of UA nanoparticle dried by MFD. The Page model can better simulate the drying kinetics of chitosan nanoparticles dried by MFD, and LF-NMR technology can monitor the changes in water status of UA nanoparticles. The results revealed that LF-NMR can monitor the changes of water in UA nanoparticles during the drying process. Keywords: microwave, drying, chitosan nanoparticles, water distribution DOI: 10.25165/j.ijabe.20231604.7519 Citation: Ren X, Duan X, Cao W W, Zhao L J, Ren G Y, Liu P P. Drying curve simulation and LF-NMR online monitor of water state in ursolic acid loaded chitosan nanoparticles during microwave freeze drying. Int J Agric & Biol Eng, 2023; 16(4): 263－268.

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载熊果酸壳聚糖纳米颗粒微波冷冻干燥过程中的干燥曲线模拟及LF-NMR在线监测

采用低场核磁共振(LF-NMR)技术研究了负载熊果酸(UA)的壳聚糖纳米颗粒在微波冷冻干燥(MFD)过程中不同状态水分的变化，并应用6个薄层模型模拟了壳聚糖纳米颗粒的干燥动力学。在不同的微波功率密度(1 W/g、2 W/g和4 W/g)下对UA纳米颗粒进行干燥。结果表明，在新鲜的UA纳米颗粒中检测到三种不同横向弛豫时间(T2)的水组分。在不同微波功率密度下，水的T2弛豫时间随干燥时间的增加而显著减小。在壳聚糖纳米颗粒干燥过程中，不同状态的水分相互迁移转化。数学模型分析表明，Page模型能较好地描述UA纳米颗粒的MFD干燥过程。Page模型可以较好地模拟MFD干燥的壳聚糖纳米颗粒的干燥动力学，LF-NMR技术可以监测UA纳米颗粒的水分状态变化。结果表明，LF-NMR可以监测UA纳米颗粒干燥过程中水分的变化。关键词:微波，干燥，壳聚糖纳米颗粒，水分分布[DOI: 10.25165/ j.j ijabe.20231604.7519]引用本文:任鑫，段鑫，曹伟伟，赵丽娟，任国勇，刘鹏鹏。负载熊果酸的壳聚糖纳米颗粒微波冷冻干燥过程中水分状态的干燥曲线模拟及低频核磁共振在线监测。农业与生物工程学报，2023;16(4): 263－268.

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来源期刊

International Journal of Agricultural and Biological Engineering AGRICULTURAL ENGINEERING-

CiteScore

4.30

自引率

12.50%

发文量

审稿时长

24 weeks

期刊介绍： International Journal of Agricultural and Biological Engineering (IJABE, https://www.ijabe.org) is a peer reviewed open access international journal. IJABE, started in 2008, is a joint publication co-sponsored by US-based Association of Agricultural, Biological and Food Engineers (AOCABFE) and China-based Chinese Society of Agricultural Engineering (CSAE). The ISSN 1934-6344 and eISSN 1934-6352 numbers for both print and online IJABE have been registered in US. Now, Int. J. Agric. & Biol. Eng (IJABE) is published in both online and print version by Chinese Academy of Agricultural Engineering.