Anna Alioto, Carlo Rossi, Simona Capano, Alessandra Amato, Sara Baldassano, Andrea Pagliaro, Giulia Lauriello, Szymon Kuliś, Patrizia Proia
{"title":"Biochemical assessment of insulin and vitamin D levels in obese adolescents after diet and physical activity: A retrospective observational study","authors":"Anna Alioto, Carlo Rossi, Simona Capano, Alessandra Amato, Sara Baldassano, Andrea Pagliaro, Giulia Lauriello, Szymon Kuliś, Patrizia Proia","doi":"10.2478/bhk-2023-0028","DOIUrl":null,"url":null,"abstract":"Abstract Study aim : Obesity is a serious public health problem that has spread over the past 40 years in industrialized countries. This condition can predispose to the onset of several chronic diseases for instance hyperlipidemia which is involved in multiple signaling pathways for bone homeostasis. There is a communication between adipose tissue and bone, which can regulate each other through feedback mechanisms including glucose consumption by bone, also regulating insulin levels. In our observational study, we analyzed the effects of low-impact training, particularly swimming, combined with a mediterranean diet on obese pre-adolescents. Material and methods : Six-month of an observational study was performed involving twenty pre-adolescents aged between 8 and 12 years with diagnosed obesity with z-BMI >2, according to the World Health Organization guidelines. Results : The assessment was carried out at the beginning of the intervention (T0) and at the end of treatment (T1). All participants were randomly assigned to either: the control group (CG) just followed the mediterranean diet whilst the experimental group (EG) over the mediterranean diet followed a planned physical activity. The results showed statistically significant differences between T0 and T1 in both CG and EG, especially concerning 1,25(OH) 2 D and insulin levels. However, the differences were more impressive in EG (1,25(OH) 2 D 9.27 vs 25.64; Insulin 29.31 vs 12.66) compared with CG (1,25(OH) 2 D 8.7 vs 13.7; Insulin 28.45 vs 22.76). Conclusions : In conclusion, these results showed the importance of diet and low-impact exercise intervention to improve pre-adolescent’s health especially those with obesity.","PeriodicalId":44223,"journal":{"name":"Biomedical Human Kinetics","volume":"66 1","pages":"0"},"PeriodicalIF":0.8000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical Human Kinetics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2478/bhk-2023-0028","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract Study aim : Obesity is a serious public health problem that has spread over the past 40 years in industrialized countries. This condition can predispose to the onset of several chronic diseases for instance hyperlipidemia which is involved in multiple signaling pathways for bone homeostasis. There is a communication between adipose tissue and bone, which can regulate each other through feedback mechanisms including glucose consumption by bone, also regulating insulin levels. In our observational study, we analyzed the effects of low-impact training, particularly swimming, combined with a mediterranean diet on obese pre-adolescents. Material and methods : Six-month of an observational study was performed involving twenty pre-adolescents aged between 8 and 12 years with diagnosed obesity with z-BMI >2, according to the World Health Organization guidelines. Results : The assessment was carried out at the beginning of the intervention (T0) and at the end of treatment (T1). All participants were randomly assigned to either: the control group (CG) just followed the mediterranean diet whilst the experimental group (EG) over the mediterranean diet followed a planned physical activity. The results showed statistically significant differences between T0 and T1 in both CG and EG, especially concerning 1,25(OH) 2 D and insulin levels. However, the differences were more impressive in EG (1,25(OH) 2 D 9.27 vs 25.64; Insulin 29.31 vs 12.66) compared with CG (1,25(OH) 2 D 8.7 vs 13.7; Insulin 28.45 vs 22.76). Conclusions : In conclusion, these results showed the importance of diet and low-impact exercise intervention to improve pre-adolescent’s health especially those with obesity.
摘要研究目的:肥胖是一个严重的公共卫生问题,在过去的40年里在工业化国家蔓延。这种情况可导致多种慢性疾病的发生,例如高脂血症,它涉及骨稳态的多种信号通路。脂肪组织和骨骼之间有一种交流,它们可以通过反馈机制相互调节,包括骨骼消耗葡萄糖,也调节胰岛素水平。在我们的观察性研究中,我们分析了低强度训练,特别是游泳,结合地中海饮食对青春期前肥胖的影响。材料和方法:根据世界卫生组织的指导方针,对20名年龄在8至12岁之间的学龄前儿童进行了为期6个月的观察性研究,这些儿童被诊断为z-BMI >2型肥胖。结果:在干预开始(T0)和治疗结束(T1)时进行评估。所有参与者都被随机分配到:对照组(CG)只遵循地中海饮食,而实验组(EG)遵循地中海饮食计划的体育活动。结果显示,T0和T1在CG和EG方面具有统计学意义,特别是在1,25(OH) 2 D和胰岛素水平方面。然而,EG (1,25(OH) 2 D) (9.27 vs 25.64;胰岛素29.31 vs 12.66)与CG (1,25(OH) 2d 8.7 vs 13.7;胰岛素28.45 vs 22.76)。结论:综上所述,这些结果表明饮食和低强度运动干预对改善青春期前儿童健康的重要性,尤其是肥胖儿童。
期刊介绍:
The leading idea is the health-directed quality of life. The journal thus covers many biomedical areas related to physical activity, e.g. physiology, biochemistry, biomechanics, anthropology, medical issues associated with physical activities, physical and motor development, psychological and sociological issues associated with physical activities, rehabilitation, health-related sport issues and fitness, etc.