{"title":"ALUM CATALYZED AN ECO-FRIENDLY SYNTHESIS OF BENZYLIDENE MALONONITRILE AND BENZYLIDENE BARBITURIC ACID DERIVATIVES IN AQUEOUS MEDIUM","authors":"B. P. Koli, None R. P. Gore","doi":"10.31788/rjc.2023.1638394","DOIUrl":null,"url":null,"abstract":"Alum-catalyzed Knoevenagel reaction of substituted aromatic aldehydes and active methylene compounds such as malononitrile and barbituric acid using green, eco-friendly solvent, water was developed. The protocol is practically simple and found efficient. The condensation is carried out in a short reaction time and the desired products are obtained in excellent yields. Furthermore, The catalyst utilized is readily accessible, cost-effective, environmentally friendly, and safe. The derivatives are among the most frequently used intermediate in heterocyclic synthesis. The synthesized benzylidene derivatives were characterized by spectral analysis","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"31 1","pages":"0"},"PeriodicalIF":0.5000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rasayan Journal of Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31788/rjc.2023.1638394","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"EDUCATION & EDUCATIONAL RESEARCH","Score":null,"Total":0}
引用次数: 0
Abstract
Alum-catalyzed Knoevenagel reaction of substituted aromatic aldehydes and active methylene compounds such as malononitrile and barbituric acid using green, eco-friendly solvent, water was developed. The protocol is practically simple and found efficient. The condensation is carried out in a short reaction time and the desired products are obtained in excellent yields. Furthermore, The catalyst utilized is readily accessible, cost-effective, environmentally friendly, and safe. The derivatives are among the most frequently used intermediate in heterocyclic synthesis. The synthesized benzylidene derivatives were characterized by spectral analysis
期刊介绍:
RASĀYAN Journal of Chemistry [RJC] signifies a confluence of diverse streams of chemistry to stir up the cerebral powers of its contributors and readers. By introducing the journal by this name, we humbly intent to provide an open platform to all researchers, academicians and readers to showcase their ideas and research findings among the people of their own fraternity and to share their vast repository of knowledge and information. The journal seeks to embody the spirit of enquiry and innovation to augment the richness of existing chemistry literature and theories. We also aim towards making this journal an unparalleled reservoir of information and in process aspire to inculcate and expand the research aptitude.