Green fabrication of PHBV microbeads using a dimethyl isosorbide solvent for skin exfoliators†

IF 10.6 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Green Chemistry Pub Date : 2023-11-27 Epub Date: 2023-11-09 DOI:10.1039/d3gc03214k

Xianzhu You , Yating Zhou , Xuru Jin , Sheng Xiang , Xiaopeng Pei , Hua Zhou , Zhiyong Liao , Ying Tan

{"title":"Green fabrication of PHBV microbeads using a dimethyl isosorbide solvent for skin exfoliators†","authors":"Xianzhu You , Yating Zhou , Xuru Jin , Sheng Xiang , Xiaopeng Pei , Hua Zhou , Zhiyong Liao , Ying Tan","doi":"10.1039/d3gc03214k","DOIUrl":null,"url":null,"abstract":"<div><p>Traditional petroleum-based microbeads in personal care products are potentially harmful to the ecological environment and human health due to their non-biodegradability. Thus, it is essential to produce eco-friendly microbeads to replace the traditional ones. In this work, a facile and green method was used to manufacture biodegradable poly(3-hydroxybutyrate-<em>co</em>-3-hydroxyvalerate) (PHBV) microbeads for application in skin exfoliators. The PHBV microbeads were rapidly fabricated <em>via</em> a solvent exchange method wherein dimethyl isosorbide (DMI) acted as a green solvent and a polysorbate 80 aqueous solution was used as the antisolvent. The polymer solution concentration can reach a high of 15 wt%, enabling scalable production. The microbeads were biocompatible and harmless to both plants and aquatic organisms. Moreover, they were degradable in water environments containing microbes yet stable during storage in microbe-free water. Additionally, PHBV microbeads demonstrated excellent skin cleaning efficiency compared to other commercial materials. Therefore, as additives in exfoliation products, these eco-friendly PHBV microbeads have the potential to replace traditional petroleum-based microbeads.</p></div>","PeriodicalId":78,"journal":{"name":"Green Chemistry","volume":"25 23","pages":"Pages 9948-9958"},"PeriodicalIF":10.6000,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Green Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1463926223008695","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/11/9 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

Traditional petroleum-based microbeads in personal care products are potentially harmful to the ecological environment and human health due to their non-biodegradability. Thus, it is essential to produce eco-friendly microbeads to replace the traditional ones. In this work, a facile and green method was used to manufacture biodegradable poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microbeads for application in skin exfoliators. The PHBV microbeads were rapidly fabricated via a solvent exchange method wherein dimethyl isosorbide (DMI) acted as a green solvent and a polysorbate 80 aqueous solution was used as the antisolvent. The polymer solution concentration can reach a high of 15 wt%, enabling scalable production. The microbeads were biocompatible and harmless to both plants and aquatic organisms. Moreover, they were degradable in water environments containing microbes yet stable during storage in microbe-free water. Additionally, PHBV microbeads demonstrated excellent skin cleaning efficiency compared to other commercial materials. Therefore, as additives in exfoliation products, these eco-friendly PHBV microbeads have the potential to replace traditional petroleum-based microbeads.

Abstract Image

查看原文本刊更多论文

用二甲基异山梨酯溶剂绿色制备皮肤去角质用PHBV微珠

PHBV微珠采用环保方式生产，具有生态友好、生物相容性好、对植物和水生生物无害、可降解等特点。它们表现出优异的皮肤清洁效率，证明了它们取代传统石油基微珠的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Green Chemistry 化学-化学综合

CiteScore

16.10

自引率

7.10%

发文量

677

审稿时长

1.4 months

期刊介绍： Green Chemistry is a journal that provides a unique forum for the publication of innovative research on the development of alternative green and sustainable technologies. The scope of Green Chemistry is based on the definition proposed by Anastas and Warner (Green Chemistry: Theory and Practice, P T Anastas and J C Warner, Oxford University Press, Oxford, 1998), which defines green chemistry as the utilisation of a set of principles that reduces or eliminates the use or generation of hazardous substances in the design, manufacture and application of chemical products. Green Chemistry aims to reduce the environmental impact of the chemical enterprise by developing a technology base that is inherently non-toxic to living things and the environment. The journal welcomes submissions on all aspects of research relating to this endeavor and publishes original and significant cutting-edge research that is likely to be of wide general appeal. For a work to be published, it must present a significant advance in green chemistry, including a comparison with existing methods and a demonstration of advantages over those methods.