Medicinal Uses of Nitrogen Group Containing Secondary Metabolites: A Review

O. A. Ushie, E. O. Ochepo, P. Y. Nkom, M. A. Ago, J. Gani
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Abstract

In the history of humanity plants have always existed as a source of health benefits to living things. These plants produce non-nutritive chemicals that have protective or disease preventive properties. These plants produce a necessary wide range of primary and secondary metabolites that have antimicrobial and antifungal properties. The primary metabolites prominently function in the growth, development, and reproduction of cells. The primary metabolites perform their functions as molecules signaling to trigger defense response. The secondary metabolites are produced by plants and used as their defense mechanism and harnessed by humans for medicinal use because of their unique pharmacological properties. The secondary metabolites are generally small organic molecules produced by plants that are not essential for their growth, development and reproduction but are used as defense mechanism by these plants. Although these secondary metabolites are not essential for plant growth, they are very essential for the health, nutrition, and economics of human societies, the main secondary metabolites are nitrogen group compounds found are in alkaloids, glycosides and non-protein. Alkaloids play a very important role due to their medicinal properties and can be used as analgesic, stimulants, anti-viral and anti-inflammatory agents etc.
含次生代谢物氮基团的药用研究进展
在人类历史上,植物一直是生物健康益处的来源。这些植物产生的非营养性化学物质具有保护或预防疾病的特性。这些植物产生必要的广泛的初级和次级代谢物,具有抗菌和抗真菌的特性。初级代谢物在细胞的生长、发育和繁殖中起着重要的作用。初级代谢物发挥分子信号的功能,触发防御反应。次生代谢物是植物自身产生的一种防御机制,因其独特的药理特性而被人类利用。次生代谢物一般是植物产生的有机小分子,不是植物生长发育和繁殖所必需的,但被植物用作防御机制。虽然这些次生代谢物不是植物生长所必需的,但它们对人类社会的健康、营养和经济至关重要,主要的次生代谢物是存在于生物碱、糖苷和非蛋白质中的氮基化合物。生物碱具有重要的药用价值,可作为止痛剂、兴奋剂、抗病毒和抗炎剂等。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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