Antibacterial effects of fresh onion (Allium cepa L.) bulbs against clinical bacteria

Patience O. Adomi, Mamuyovwi J. Nana
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Abstract

The purpose of study was to determine the effects of fresh onion bulbs extracts on pathogenic bacteria in an attempt to seek active components presentin the onion bulbs. Standard procedures were used for plant extraction and antibacterial susceptibility tests. The extracts were active against Escherichia coli, Staphylococcus aureus, Streptococcus Spp and Enterococcus Spp. while Pseudomonas aeruginosa and Bacillus subtilis were resistant to plant extracts and standard antibiotics. Minimum inhibitory concentration were 25mg/ml and 50mg/ml respectively for ethanol and methanol extracts for E. coli and Streptococcus Spp. The phytochemical results indicated the presence of saponins phenols, tannins, steroid, alkaloids, cardiac glycosides and flavonoid. Anthraqinone and terpenoid were absent. Conclusively, water extracts of fresh onion bulbs was not potent against clinical isolates however ethanol and methanol extracts were active. Fresh onions bulb extracts contained low concentrations of phytochemical compounds.
鲜洋葱(Allium cepa L.)鳞茎对临床细菌的抑菌作用
本研究的目的是测定新鲜洋葱提取物对病原菌的影响,试图寻找洋葱中存在的有效成分。采用标准程序进行植物提取和抗菌药敏试验。提取物对大肠埃希菌、金黄色葡萄球菌、链球菌和肠球菌均有活性,铜绿假单胞菌和枯草芽孢杆菌对植物提取物和标准抗生素均有抗性。乙醇和甲醇提取物对大肠杆菌和链球菌的最低抑菌浓度分别为25mg/ml和50mg/ml。植物化学结果表明,乙醇和甲醇提取物中含有皂苷、酚类、单宁、甾体、生物碱、心苷和类黄酮。不含蒽醌和萜类。综上所述,鲜洋葱水提物对临床分离株无明显的抑制作用,而乙醇和甲醇提取物对临床分离株有一定的抑制作用。新鲜洋葱球茎提取物含有低浓度的植物化学化合物。
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