The effects of hematological parameters and anticoagulant/antiaggregant use on surgical outcomes in acute subdural hematoma

Medical Science and Discovery Pub Date : 2023-09-27 DOI:10.36472/msd.v10i9.1043

Tuba Bulduk, Havva Nur Karaaslan

{"title":"The effects of hematological parameters and anticoagulant/antiaggregant use on surgical outcomes in acute subdural hematoma","authors":"Tuba Bulduk, Havva Nur Karaaslan","doi":"10.36472/msd.v10i9.1043","DOIUrl":null,"url":null,"abstract":"Objective: This study aims to investigate the effect of hematologic parameters including International Normalized Ratio (INR), platelet (Plt), hemoglobin (Hb), hematocrit (Htc), mean corpuscular volume (MCV), leukocyte, neutrophil, lymphocyte, C-Reactive Protein (CRP) on the outcomes of surgical treatment of acute subdural hematoma. Material and Methods: The file data of 31 cases who were operated on with the diagnosis of Acute Subdural Hematoma (ASDH) at the Private Ankara Güven Hospital Neurosurgery Clinic between 01.01.2019 and 31.12.2021 were examined retrospectively. The ages, genders, history of anticoagulant/antiaggregant use, INR, platelet, hemoglobin, hematocrit, leukocyte, and CRP values of patients were recorded, and their relationships with re-bleeding, number of surgeries performed, and mortality were evaluated statistically. Results: The study was conducted with a total of 31 cases (35.5% (n=11) female and 64.5% (n=20) male). The average age of the cases was 72 (45-93). A single surgery was performed in 23 cases (74.2%), 8 patients (25.8%) were operated on again because of re-bleeding, and 9 of the cases (29%) died following the surgery. Among the 9 patients who died, 5 (55.5%) underwent single surgery and 4 (44.5%) underwent more than one surgery. The number of cases not using pre-operative anticoagulants/antiaggregants was 10 (32.3%), 9 (29%) patients were using anticoagulants, 7 patients (22.6%) were using single antiaggregant, and 5 patients (16.1%) were using dual antiaggregants. It was detected as statistically significant that the preoperative INR, leukocyte, and neutrophil counts of the patients who underwent multiple surgeries were detected to be higher than those of ASDH patients who underwent single surgery. Conclusion: Although pre-operative INR, leukocyte, and neutrophil elevation are not associated with mortality, these parameters can be associated with the requirement for re-surgery because of re-bleeding. Key words: re-bleeding, subdural hematoma, mortality, leukocyte, neutrophil","PeriodicalId":18486,"journal":{"name":"Medical Science and Discovery","volume":"41 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Science and Discovery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36472/msd.v10i9.1043","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: This study aims to investigate the effect of hematologic parameters including International Normalized Ratio (INR), platelet (Plt), hemoglobin (Hb), hematocrit (Htc), mean corpuscular volume (MCV), leukocyte, neutrophil, lymphocyte, C-Reactive Protein (CRP) on the outcomes of surgical treatment of acute subdural hematoma. Material and Methods: The file data of 31 cases who were operated on with the diagnosis of Acute Subdural Hematoma (ASDH) at the Private Ankara Güven Hospital Neurosurgery Clinic between 01.01.2019 and 31.12.2021 were examined retrospectively. The ages, genders, history of anticoagulant/antiaggregant use, INR, platelet, hemoglobin, hematocrit, leukocyte, and CRP values of patients were recorded, and their relationships with re-bleeding, number of surgeries performed, and mortality were evaluated statistically. Results: The study was conducted with a total of 31 cases (35.5% (n=11) female and 64.5% (n=20) male). The average age of the cases was 72 (45-93). A single surgery was performed in 23 cases (74.2%), 8 patients (25.8%) were operated on again because of re-bleeding, and 9 of the cases (29%) died following the surgery. Among the 9 patients who died, 5 (55.5%) underwent single surgery and 4 (44.5%) underwent more than one surgery. The number of cases not using pre-operative anticoagulants/antiaggregants was 10 (32.3%), 9 (29%) patients were using anticoagulants, 7 patients (22.6%) were using single antiaggregant, and 5 patients (16.1%) were using dual antiaggregants. It was detected as statistically significant that the preoperative INR, leukocyte, and neutrophil counts of the patients who underwent multiple surgeries were detected to be higher than those of ASDH patients who underwent single surgery. Conclusion: Although pre-operative INR, leukocyte, and neutrophil elevation are not associated with mortality, these parameters can be associated with the requirement for re-surgery because of re-bleeding. Key words: re-bleeding, subdural hematoma, mortality, leukocyte, neutrophil

查看原文本刊更多论文

血液学参数和抗凝/抗聚集剂使用对急性硬膜下血肿手术结果的影响

目的:探讨国际标准化比率(INR)、血小板(Plt)、血红蛋白(Hb)、红细胞压积(Htc)、平均红细胞体积(MCV)、白细胞、中性粒细胞、淋巴细胞、c反应蛋白(CRP)等血液学指标对急性硬膜下血肿手术治疗效果的影响。材料与方法:回顾性分析2019年1月1日至2021年12月31日在私立安卡拉g ven医院神经外科诊所以急性硬膜下血肿(ASDH)诊断进行手术的31例患者的档案资料。记录患者的年龄、性别、抗凝/抗聚史、INR、血小板、血红蛋白、红细胞压积、白细胞和CRP值，并对其与再出血、手术次数和死亡率的关系进行统计学评价。结果:共纳入31例患者，其中女性11例(35.5%)，男性20例(64.5%)。平均年龄72岁(45 ~ 93岁)。单次手术23例(74.2%)，因再出血再次手术8例(25.8%)，术后死亡9例(29%)。9例死亡患者中，5例(55.5%)行单次手术，4例(44.5%)行一次以上手术。术前未使用抗凝/抗聚集药物10例(32.3%)，使用抗凝药物9例(29%)，使用单一抗聚集药物7例(22.6%)，使用双重抗聚集药物5例(16.1%)。多次手术患者术前INR、白细胞、中性粒细胞计数高于单次手术ASDH患者，有统计学意义。结论:虽然术前INR、白细胞和中性粒细胞升高与死亡率无关，但这些参数可能与因再出血而需要再次手术有关。关键词:再出血，硬膜下血肿，死亡率，白细胞，中性粒细胞

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Medical Science and Discovery

自引率

0.00%

发文量