Polypoid Basal Cell Carcinoma on the Right Axillary Region of a Young Lady Four Weeks Gestation: A Case Report

Amirsaleh Abdollahi, Armaghan Kazeminejad, Nooshin Izadpanahi, Somayeh Sheidaei, Mohammad Zahedi
{"title":"Polypoid Basal Cell Carcinoma on the Right Axillary Region of a Young Lady Four Weeks Gestation: A Case Report","authors":"Amirsaleh Abdollahi, Armaghan Kazeminejad, Nooshin Izadpanahi, Somayeh Sheidaei, Mohammad Zahedi","doi":"10.19080/gjorm.2023.09.555765","DOIUrl":null,"url":null,"abstract":"Basal Cell Carcinoma (BCC) is the most common skin neoplasm of various types. It has various clinical forms, mainly known as nodular, superficial, and morphea. Other less prevalent forms include polypoid, pore-like, and Jacobi ulcers. Polypoid BCC is rarely observed in individuals and has remarkable clinical features, such as being pedunculated and connected to the skin by a stalk; the BCC incidence is more in women than men and correlates directly with age, as it is reported to be <15% in patients below 40 years, so it is not frequently observed among young adults. In this case, we report one type of BCC presented as a skin tag. A 21-year-old young lady, four weeks gestation, was referred with a skin tag on the right axillary region. Surgical excision was performed; a histopathologic examination of the skin lesion revealed a malignant epithelial neoplasm composed of some nests of basaloid cells and an accumulation of mucin. The IHC staining, such as Bcl2, CK20, CD34, and Ki67, facilitates better evaluations. The diffuse pattern of Bcl2 in basaloid cells, the rare staining of CD34 in stromal cells, the absence of CK20, and high positivity of Ki67 in tumor cells are favored in diagnosing BCC.","PeriodicalId":92369,"journal":{"name":"Global journal of reproductive medicine","volume":"233 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Global journal of reproductive medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.19080/gjorm.2023.09.555765","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Basal Cell Carcinoma (BCC) is the most common skin neoplasm of various types. It has various clinical forms, mainly known as nodular, superficial, and morphea. Other less prevalent forms include polypoid, pore-like, and Jacobi ulcers. Polypoid BCC is rarely observed in individuals and has remarkable clinical features, such as being pedunculated and connected to the skin by a stalk; the BCC incidence is more in women than men and correlates directly with age, as it is reported to be <15% in patients below 40 years, so it is not frequently observed among young adults. In this case, we report one type of BCC presented as a skin tag. A 21-year-old young lady, four weeks gestation, was referred with a skin tag on the right axillary region. Surgical excision was performed; a histopathologic examination of the skin lesion revealed a malignant epithelial neoplasm composed of some nests of basaloid cells and an accumulation of mucin. The IHC staining, such as Bcl2, CK20, CD34, and Ki67, facilitates better evaluations. The diffuse pattern of Bcl2 in basaloid cells, the rare staining of CD34 in stromal cells, the absence of CK20, and high positivity of Ki67 in tumor cells are favored in diagnosing BCC.
年轻女性妊娠四周右腋窝区息肉样基底细胞癌1例报告
基底细胞癌是各种类型中最常见的皮肤肿瘤。它有多种临床表现,主要有结节性、浅表性和硬膜性。其他不太常见的形式包括息肉样溃疡、孔样溃疡和雅可比溃疡。息肉样BCC在个体中很少观察到,具有显著的临床特征,如有带梗,通过茎与皮肤相连;BCC在女性中的发病率高于男性,且与年龄直接相关,据报道,40岁以下患者的BCC发病率为15%,因此在年轻人中并不常见。在这种情况下,我们报告一种类型的BCC表现为皮赘。一位21岁的年轻女士,怀孕4周,在右腋窝区域出现皮肤赘。手术切除;皮肤病变的组织病理学检查显示一个恶性上皮肿瘤,由一些基底样细胞巢和粘蛋白堆积组成。免疫组化染色,如Bcl2、CK20、CD34和Ki67,有助于更好的评估。基底细胞中Bcl2的弥漫性、基质细胞中CD34的罕见染色、肿瘤细胞中CK20的缺失以及Ki67的高阳性均有利于BCC的诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信