Gerhard Schmidt, Erik Engelhardt, Eric Elzenheimer, Johannes Hoffman, Tobias Schmidt, Adrian Zaman, Norbert Frey
{"title":"A Concept for Myocardial Current Density Estimation with Magnetoelectric Sensors","authors":"Gerhard Schmidt, Erik Engelhardt, Eric Elzenheimer, Johannes Hoffman, Tobias Schmidt, Adrian Zaman, Norbert Frey","doi":"10.1515/cdbme-2023-1023","DOIUrl":null,"url":null,"abstract":"Abstract In this paper we present a novel noninvasive approach to estimate current densities in the heart from magnetocardiography. The proposed algorithm uses nested optimization to model current densities in equally-sized voxels of myocardial tissue. First-order Thiran all-pass filters are used to describe the propagation between voxels.We demonstrate feasibility of the algorithm for a noise-free single-layer simulation. However, challenges remain, such as addressing measurement noise and optimizing propagation velocity. Overall, this approach has the potential to complement or replace invasive catheter-based electrophysiological studies for localization of arrhythmogenic tissue.","PeriodicalId":10739,"journal":{"name":"Current Directions in Biomedical Engineering","volume":"96 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Directions in Biomedical Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1515/cdbme-2023-1023","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Engineering","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract In this paper we present a novel noninvasive approach to estimate current densities in the heart from magnetocardiography. The proposed algorithm uses nested optimization to model current densities in equally-sized voxels of myocardial tissue. First-order Thiran all-pass filters are used to describe the propagation between voxels.We demonstrate feasibility of the algorithm for a noise-free single-layer simulation. However, challenges remain, such as addressing measurement noise and optimizing propagation velocity. Overall, this approach has the potential to complement or replace invasive catheter-based electrophysiological studies for localization of arrhythmogenic tissue.