Síndrome inflamatorio multisistémico pediátrico en paciente con oxigenación por membrana extracorpórea, reporte de un caso

Mauricio Valencia Garcia , Yolima Porto Jaramillo , Jhojan Sebastian Herrera Vargas , Alfredo Hernández Ruiz , Roberto Gaitan Luque , Neil Miguel Daza Alaracon
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Abstract

Pediatric multisystem inflammatory syndrome temporally associated with COVID-19 is a rare presentation of SARS-CoV-2 infection. Its most common manifestation is cardiogenic shock, with a high percentage of patients requiring vasoactive and inotropic support.

Occasionally, the myocardial dysfunction can be severe enough to result in death. Therapies such as extracorporeal membrane oxygenation (ECMO) provide a transient support option for recovery; however, it is an underutilized tool.

In this article, we present the case of an adolescent who initially presented with gastrointestinal symptoms and fever, who subsequently developed refractory cardiogenic shock attributed to a systemic inflammatory syndrome associated with COVID-19. The presence of SARS-CoV-2 was identified through tracheal aspirate, and due to hemodynamic instability, the patient received ECMO therapy along with steroid medications, immunomodulators, and inotropes. After one week, the patient recovered ventricular function with a favorable outcome.

In conclusion, ECMO therapy in pediatric patients with systemic inflammatory syndrome associated with COVID-19 may contribute to improved survival. However, the low utilization of this therapy and limited reporting in the literature lead to deficiencies in the evidence supporting its implementation.

体外膜氧合患者的儿科多系统炎症综合征,病例报告。
小儿多系统炎症综合征与 COVID-19 在时间上相关,是 SARS-CoV-2 感染的一种罕见表现。其最常见的表现是心源性休克,需要血管活性和肌力支持的患者比例很高。体外膜肺氧合(ECMO)等疗法为患者的康复提供了一种短暂的支持选择;然而,它是一种未得到充分利用的工具。在本文中,我们介绍了一例青少年病例,该患者最初表现为胃肠道症状和发热,随后因与 COVID-19 相关的全身炎症综合征而出现难治性心源性休克。由于血流动力学不稳定,患者在接受类固醇药物、免疫调节剂和肌注的同时接受了 ECMO 治疗。总之,对患有 COVID-19 全身炎症综合征的儿科患者进行 ECMO 治疗可能有助于提高生存率。总之,对 COVID-19 全身炎症综合征的小儿患者进行 ECMO 治疗可能有助于改善生存率,但由于该疗法的使用率较低,且文献报道有限,导致支持该疗法实施的证据不足。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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