A 2D GaAs-Based Photonic Crystal Biosensor for Malaria Detection

IF 1.3 Q3 ENGINEERING, MULTIDISCIPLINARY
None Manjunatha N, None Sarika Raga, None Sanjay Kumar Gowre, None Hameed Miyan
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引用次数: 0

Abstract

Gallium arsenide (GaAs) composite semi-conductive rods with an air background lattice act as the building blocks for the photonic crystal structure used of a biosensor. The study presents a biosensor of a two-rod nano-cavity for identifying distinct stages of plasmodium falciparum in red blood cells (RBCs) in the early detection of malaria. The proposed biosensor enables the creation of a label-free biosensing environment in which optical and dispersion properties are investigated using plane wave expansion (PWE) and finite-difference time-domain (FDTD) techniques. The biosensor, with a sensing region for an analyte, is utilized to detect a change in refractive index to differentiate between normal RBCs and plasmodium falciparum-infected cells. The results show that the biosensor has a high sensitivity of 798.143 nm/RIU, a high Q-factor of 9881.926, a low detection limit (δ) of 222.4 × 10-6 RIU, a high FOM of 4496.079 RIU-1, and a compact area of 46.14 µm2.
用于疟疾检测的二维gaas光子晶体生物传感器
具有空气背景晶格的砷化镓(GaAs)复合半导电棒可作为生物传感器光子晶体结构的基石。该研究提出了一种双棒纳米腔生物传感器,用于在疟疾早期检测中识别红细胞(rbc)中恶性疟原虫的不同阶段。所提出的生物传感器能够创建一个无标记的生物传感环境,其中使用平面波扩展(PWE)和时域有限差分(FDTD)技术研究光学和色散特性。该生物传感器具有用于分析物的传感区域,用于检测折射率的变化,以区分正常红细胞和恶性疟原虫感染的细胞。结果表明,该传感器灵敏度为798.143 nm/RIU, q因子为9881.926,检出限δ为222.4 × 10-6 RIU, FOM为4496.079 RIU-1,紧凑面积为46.14µm2。
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来源期刊
CiteScore
2.80
自引率
0.00%
发文量
18
审稿时长
12 weeks
期刊介绍: The IJETI journal focus on the field of engineering and technology Innovation. And it publishes original papers including but not limited to the following fields: Automation Engineering Civil Engineering Control Engineering Electric Engineering Electronic Engineering Green Technology Information Engineering Mechanical Engineering Material Engineering Mechatronics and Robotics Engineering Nanotechnology Optic Engineering Sport Science and Technology Innovation Management Other Engineering and Technology Related Topics.
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