Vitamin B<sub>12</sub> – a scoping review for Nordic Nutrition Recommendations 2023

IF 3.5 4区 医学 Q2 FOOD SCIENCE & TECHNOLOGY
Anne-Lise Bjørke Monsen, Vegard Lysne
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引用次数: 0

Abstract

Vitamin B12 (cobalamin) is essential for normal metabolic function, and even moderate deficiency of this vitamin has negative health effects. Vitamin B12 is found in animal foods, and as vegetarian diets are increasingly popular in Western countries, one might expect a higher prevalence of vitamin B12 deficiency in the Nordic population. Setting recommendations for vitamin B12 intake has proven to be difficult, as uptake of vitamin B12 varies substantially, the clinical deficiency symptoms are often diffuse, and there is no clear agreement on the decision limits for vitamin B12 deficiency. Vitamin B12 deficiency is reported to be particularly common among pregnant women and infants, despite the fact that less than 1% of Norwegian pregnant women have a cobalamin intake below the Nordic Nutrition Recommendations 2012-recommended level of 2.0 µg/day. In addition, the assumption that breast milk contains sufficient vitamin B12 for optimal health and neurodevelopment during the first 6 months of life does not comply with the high prevalence of insufficient vitamin B12 status in this age group. Recommended intakes of vitamin B12 vary among age groups and must be based on markers of cobalamin status, indicating an optimal intracellular biochemical status, and not merely absence of clinical signs of vitamin B12 deficiency.
维生素B< sub> 12 & lt; / sub>-《北欧营养建议2023》的范围审查
维生素B12(钴胺素)是正常代谢功能所必需的,即使是适度缺乏这种维生素也会对健康产生负面影响。维生素B12存在于动物性食物中,随着素食在西方国家越来越受欢迎,人们可能会认为北欧人口中维生素B12缺乏症的发病率更高。制定维生素B12摄入量的建议已被证明是困难的,因为维生素B12的摄入量变化很大,临床缺乏症状往往是弥漫性的,而且对维生素B12缺乏的决定限度没有明确的一致意见。据报道,维生素B12缺乏症在孕妇和婴儿中尤为普遍,尽管只有不到1%的挪威孕妇的钴胺素摄入量低于《2012年北欧营养建议》推荐的2.0微克/天的水平。此外,母乳中含有足够的维生素B12以维持婴儿出生后前6个月的最佳健康和神经发育的假设,并不符合该年龄组维生素B12缺乏的普遍情况。维生素B12的推荐摄入量因年龄组而异,必须基于钴胺素状态的标志物,表明最佳的细胞内生化状态,而不仅仅是缺乏维生素B12缺乏症的临床症状。
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来源期刊
Food & Nutrition Research
Food & Nutrition Research FOOD SCIENCE & TECHNOLOGY-NUTRITION & DIETETICS
CiteScore
5.20
自引率
9.10%
发文量
47
审稿时长
14 weeks
期刊介绍: Food & Nutrition Research is a peer-reviewed journal that presents the latest scientific research in various fields focusing on human nutrition. The journal publishes both quantitative and qualitative research papers. Through an Open Access publishing model, Food & Nutrition Research opens an important forum for researchers from academic and private arenas to exchange the latest results from research on human nutrition in a broad sense, both original papers and reviews, including: * Associations and effects of foods and nutrients on health * Dietary patterns and health * Molecular nutrition * Health claims on foods * Nutrition and cognitive functions * Nutritional effects of food composition and processing * Nutrition in developing countries * Animal and in vitro models with clear relevance for human nutrition * Nutrition and the Environment * Food and Nutrition Education * Nutrition and Economics Research papers on food chemistry (focus on chemical composition and analysis of foods) are generally not considered eligible, unless the results have a clear impact on human nutrition. The journal focuses on the different aspects of nutrition for people involved in nutrition research such as Dentists, Dieticians, Medical doctors, Nutritionists, Teachers, Journalists and Manufacturers in the food and pharmaceutical industries.
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