An outcome study on conservative management of spinal tuberculosis

Ritesh Runu, Nischay Kaushik, Ayush Choudhary, BimleshKumar Bimal, Wasim Ahmed, Nishant Kashyap
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Abstract

Introduction: Spinal tuberculosis (TB) is a serious form of extrapulmonary TB which if left untreated can be fatal due to vertebral body collapse causing cord compression, neurological deficit, and visceral complications. It is mainly treated by antitubercular therapy and bracing. If required, debridement and fixation is also done. With the advent of magnetic resonance imaging and other diagnostics, spinal TB can be detected early. With early diagnosis, we want to assess the outcome of conservative management of spinal TB in the population of Bihar. Materials and Methods: After ethical clearance, a prospective study on 60 patients with spinal TB was conducted. The diagnosis was based on clinical signs and symptoms, serological tests, radiological tests, and histological confirmation. Antitubercular therapy was started and regular assessment was done clinically, serologically, and radiologically. Based on all three parameters, the therapy was stopped once the patient had healed TB. Results: Twenty-eight patients out of 60 had a neurological deficit, and after treatment, 20 patients completely recovered. Kyphosis was seen in 5 patients at presentation and 13 patients after completion of therapy. Two patients developed scoliosis after therapy completion. None had a neurological deficit. Conclusions: Spinal TB can be effectively treated by anti-TB therapy which helps in disease extirpation and neurological improvement but does not prevent the development of spinal deformity.
脊柱结核保守治疗的结果研究
脊柱结核(TB)是肺外结核的一种严重形式,如果不及时治疗,由于椎体塌陷导致脊髓压迫、神经功能缺损和内脏并发症,可能是致命的。主要采用抗结核治疗和支具治疗。如果需要,清创和固定也要做。随着磁共振成像和其他诊断方法的出现,脊柱结核可以及早发现。在早期诊断的情况下,我们想评估比哈尔邦人群脊柱结核保守治疗的结果。材料与方法:经伦理审查,对60例脊柱结核患者进行前瞻性研究。诊断依据临床体征和症状、血清学检查、放射学检查和组织学证实。开始抗结核治疗,并定期进行临床、血清学和放射学评估。基于所有这三个参数,一旦患者治愈结核病,就停止治疗。结果:60例患者中28例出现神经功能缺损,经治疗后20例完全恢复。5例患者在就诊时出现后凸,13例患者在治疗结束后出现后凸。2例患者治疗结束后出现脊柱侧凸。没有人有神经缺陷。结论:抗结核治疗可有效治疗脊柱结核,有助于疾病的根除和神经系统的改善,但不能防止脊柱畸形的发展。
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