Carbon Dot‐Based Fluorescence Resonance Energy Transfer (FRET) Systems for Biomedical, Sensing, and Imaging Applications

IF 2.7 4区 材料科学 Q3 CHEMISTRY, PHYSICAL
Abhilash Raj Gopal, Francis Joy, Vishal Dutta, Jyothis Devasia, Ramesh Dateer, Aatika Nizam
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引用次数: 0

Abstract

Abstract Carbon dots (CDs) emerge as a potential group of photo‐luminescent nano‐materials due to their excellent optical, electrical, and chemical properties, as well as their competence in a wide range of environmental applications. CDs have unique and appealing properties such as excellent stability, low toxicity, water solubility, and derivability. When coupled with CDs, fluorescence resonance energy transfer (FRET) results in the development of highly sensitive ratiometric fluorescence sensor probes with potential applications in bio‐imaging, metal sensing, membrane dynamics, and environmental sensing. In this review, the progress and recent developments in CDs based FRET systems utilized for various environmental applications are conferred. An in‐depth description is provided regarding the numerous donor/acceptor systems which when integrated with CDs generate efficient FRET systems. The review enables researchers to identify and develop specific systems which can be utilized to generate a FRET pair with potential physico–chemical properties that aid the development of the same for various applications.

Abstract Image

碳点基荧光共振能量转移(FRET)系统用于生物医学,传感和成像应用
摘要:碳点(cd)由于其优异的光学、电学和化学性能以及在广泛的环境应用中的能力而成为一种潜在的光致发光纳米材料。CDs具有独特而吸引人的特性,如优异的稳定性、低毒性、水溶性和可衍生性。当与CDs结合时,荧光共振能量转移(FRET)导致高灵敏度比例荧光传感器探针的发展,在生物成像,金属传感,膜动力学和环境传感方面具有潜在的应用前景。在这篇综述中,介绍了用于各种环境应用的基于cd的FRET系统的进展和最新发展。深入描述了许多供体/受体系统,当与cd集成时,产生高效的FRET系统。该综述使研究人员能够识别和开发特定的系统,这些系统可用于生成具有潜在物理化学性质的FRET对,从而有助于开发各种应用。
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来源期刊
Particle & Particle Systems Characterization
Particle & Particle Systems Characterization 工程技术-材料科学:表征与测试
CiteScore
5.50
自引率
0.00%
发文量
114
审稿时长
3.0 months
期刊介绍: Particle & Particle Systems Characterization is an international, peer-reviewed, interdisciplinary journal focusing on all aspects of particle research. The journal joined the Advanced Materials family of journals in 2013. Particle has an impact factor of 4.194 (2018 Journal Impact Factor, Journal Citation Reports (Clarivate Analytics, 2019)). Topics covered include the synthesis, characterization, and application of particles in a variety of systems and devices. Particle covers nanotubes, fullerenes, micelles and alloy clusters, organic and inorganic materials, polymers, quantum dots, 2D materials, proteins, and other molecular biological systems. Particle Systems include those in biomedicine, catalysis, energy-storage materials, environmental science, micro/nano-electromechanical systems, micro/nano-fluidics, molecular electronics, photonics, sensing, and others. Characterization methods include microscopy, spectroscopy, electrochemical, diffraction, magnetic, and scattering techniques.
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