Protein nanocage engineering for Pickering emulsions and potential food applications

IF 7.9 2区化学 Q1 CHEMISTRY, PHYSICAL

Current Opinion in Colloid & Interface Science Pub Date : 2023-09-28 DOI:10.1016/j.cocis.2023.101761

Samuel Watts, Chase Jia Jing Chow, Sierin Lim

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Abstract

Protein nanocages used as emulsion stabilizing colloidal particles are opening possibilities to the design of novel delivery systems for food, pharmaceutical and cosmetic applications. Protein nanocage-stabilized emulsions are able to co-deliver hydrophilic and hydrophobic compounds. The surface chemistry of the particles is one of the factors that determines their ability to stabilize the emulsion. Hence, the importance in developing strategies to rationally tailor the nanocage surface chemistry. This contribution summarizes recent advances in protein nanocage Pickering emulsions and the methods used to modify the nanocages. It discusses future strategies that may allow the modification of protein nanocages based on current knowledge of Pickering emulsions and protein nanocage engineering technology. The characterization methods for the investigation of these protein nanocages and nanocage stabilized emulsions are described. Finally, the applications of protein nanocages for nutrient delivery in the gastrointestinal tract will be discussed. This contribution provides a perspective for future work on protein nanocage stabilized emulsions.

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用于皮克林乳液和潜在食品应用的蛋白质纳米笼工程

用作乳液稳定胶体颗粒的蛋白质纳米囊为设计食品、药品和化妆品应用领域的新型输送系统提供了可能性。经蛋白质纳米笼稳定的乳液能够同时输送亲水性和疏水性化合物。颗粒的表面化学性质是决定其稳定乳液能力的因素之一。因此，制定合理调整纳米囊表面化学性质的策略非常重要。本文总结了蛋白质纳米笼皮克林乳液的最新进展以及用于修饰纳米笼的方法。它讨论了基于目前对皮克林乳液和蛋白质纳米笼工程技术的了解，未来可能对蛋白质纳米笼进行改性的策略。介绍了研究这些蛋白质纳米笼和纳米笼稳定乳液的表征方法。最后，将讨论蛋白质纳米囊在胃肠道营养输送方面的应用。这篇论文为蛋白质纳米笼稳定乳液的未来工作提供了一个视角。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Opinion in Colloid & Interface Science 化学-物理化学

CiteScore

16.50

自引率

1.10%

发文量

审稿时长

11.3 weeks

期刊介绍： Current Opinion in Colloid and Interface Science (COCIS) is an international journal that focuses on the molecular and nanoscopic aspects of colloidal systems and interfaces in various scientific and technological fields. These include materials science, biologically-relevant systems, energy and environmental technologies, and industrial applications. Unlike primary journals, COCIS primarily serves as a guide for researchers, helping them navigate through the vast landscape of recently published literature. It critically analyzes the state of the art, identifies bottlenecks and unsolved issues, and proposes future developments. Moreover, COCIS emphasizes certain areas and papers that are considered particularly interesting and significant by the Editors and Section Editors. Its goal is to provide valuable insights and updates to the research community in these specialized areas.