Role of Nigella sativa in Preventing Oxidative Stress Damage Using Planaria as Model Organism

IF 1.2 Q4 PHARMACOLOGY & PHARMACY

Journal of Herbs, Spices and Medicinal Plants Pub Date : 2023-09-13 DOI:10.1080/10496475.2023.2255164

Sadik Aref

引用次数: 1

Abstract

Antioxidative effects of N. sativa were explored using planaria as a model organism. Planaria were cultured in water, N. sativa seed extract, hydrogen peroxide, and a combination of hydrogen peroxide and N. sativa. Planaria were decapitated and observed through stages of regeneration. N. sativa treatment increased Planarian growth, locomotion, and protein. Among hydrogen peroxide stress-induced groups, growth was 92% greater, locomotion was 26% higher, and protein was 86% greater when treated with N. sativa. N. sativa accelerated the regeneration of planaria and minimized the effects of stress. N. sativa can be a promising option for preventing neurodegenerative diseases.

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以涡虫为模式生物的黑穗病在预防氧化应激损伤中的作用

以涡虫为模式生物，探讨了油菜的抗氧化作用。将涡虫培养在水、蚕豆种子提取物、双氧水和双氧水与蚕豆的混合物中。涡虫被斩首并通过再生阶段进行观察。苜蓿处理增加了涡虫的生长、运动和蛋白质。在过氧化氢胁迫诱导组中，油菜的生长速度提高了92%，运动能力提高了26%，蛋白质含量提高了86%。sativa加速了涡虫的再生，减少了胁迫的影响。油菜可能是预防神经退行性疾病的一个有希望的选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Herbs, Spices and Medicinal Plants Medicine-Complementary and Alternative Medicine

CiteScore

3.00

自引率

0.00%

发文量

期刊介绍： The Journal of Herbs, Spices & Medicinal Plants is an essential reference filled with recent research and other valuable information associated with herbs, spices, and medicinal plants. The Journal serves as a focus point through which investigators and others may publish material of importance to the production, marketing, and utilization of these plants and associated extracts. The journal covers the following topics: growth, development, horticulture, ecology, physiology, genetics, chemistry, and economics. Original articles, review articles, and book reviews provide information of interest to an international audience of researchers, teachers, technicians, and managers involved with production and/or marketing of herbs, spices, and medicinal plants. Managers of food companies, food processing facilities, medical research laboratories, government agencies, and others interested in new chemicals, food additives, international trade, patents, and other items can easily review new findings. The Journal of Herbs, Spices & Medicinal Plants is a forum in which recent research and other information associated with herbs, spices, and medicinal plants is shared. The Journal represents a centralized database accessible by investigators within the international community that work with or have an interest in herbs, spices, and medicinal plants.