A study of thrombocytopenia in patients with alcohol withdrawal and its association with clinical complications

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-01-01 DOI:10.33545/pathol.2023.v6.i3b.541

Dr. Bansri B Patel, Dr. Sanjay V Dhotre, Dr. Hitendra Barot, Dr. Bhavesh Faldu, Dr. Amit Satasiya, Dr. Hansa Goswami

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Abstract

Background: The aim of the study is to evaluate thrombocytopenia in alcohol withdrawal symptoms (AWS) as a predictive marker for non-severe alcohol withdrawal symptoms (nAWS) to severe alcohol withdrawal symptoms (sAWS) and its relationship with liver enzymes.Methodology: A 3 months (forty-three patients) prospective study during June 2023 to August 2023 was carried out in patient admitted at B. J. Medical College with complains of symptoms related with alcohol withdrawal. Detailed history and evaluation regarding alcohol dependence along with laboratory parameters like CBC, LFT, RFT at regular intervals was carried out. On achieving the diagnostic criteria of alcohol withdrawal symptoms patients was treated and discharge.Result: During the treatment period out of 43 patients, 9 (21%) were having complains of sAWS out of which 7 had reduced platelet counts and remaining 34 (79%) were having complains of nAWS. Liver enzyme (Alanine transaminase (ALT)) was higher in 28% (12/43) of patients ranging from (42-178 IU/L) which was a significant risk factor (p

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酒精戒断患者血小板减少症及其与临床并发症的关系研究

背景:本研究的目的是评估酒精戒断症状(AWS)中血小板减少作为非严重酒精戒断症状(nAWS)到严重酒精戒断症状(sAWS)的预测指标及其与肝酶的关系。方法:于2023年6月至2023年8月对b.j.医学院收治的主诉酒精戒断相关症状的患者进行为期3个月(43例患者)的前瞻性研究。对酒精依赖进行详细的病史和评估，并定期检查CBC、LFT、RFT等实验室参数。达到酒精戒断症状诊断标准后，对患者进行治疗并出院。结果:43例患者治疗期间，9例(21%)患者出现sAWS主诉，其中7例出现血小板计数降低，34例(79%)患者出现nAWS主诉。肝酶(丙氨酸转氨酶(ALT))在(42-178 IU/L)的患者中有28%(12/43)较高，这是一个重要的危险因素(p

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International Journal of Clinical and Diagnostic Pathology

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