The laboratory perspective: Confirming the integrity of fingermark enhancement reagents

IF 1.9 4区 医学 Q2 MEDICINE, LEGAL
Roberto S.P. King, Beth McNash, Richard Wilson
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引用次数: 0

Abstract

Validation is particularly important in forensic science. Each process utilised by a forensic laboratory will undergo validation to ensure it is functioning as expected. Some pieces of equipment (hardware) will be simple to validate, and this will be conducted regularly. However, many commonly employed fingermark enhancement reagents, such as ninhydrin and 1,2-Indandione, do not have clearly defined and robust validation parameters. To that end, artificial fingermark solutions, particularly amino acid solutions, have previously been investigated as a controlled validation method, via deposition onto a substrate. Whilst amino acid reagents are important, there is also a wider group of latent fingermark constituents (targets) that require the use of other enhancement reagents within the forensic laboratory. The work presented herein seeks to expand on the concept of amino acid printing, by exploring the possibilities of depositing a sebaceous solution matrix, thereby facilitating the testing of reagents such as Oil-Red-O and Physical Developer. In addition, we present a method that extends capabilities beyond fingermark enhancement reagents for porous substrates, by developing a methodology that enables process validation of the cyanoacrylate fuming technique to be easily facilitated. These simple and effective solutions have the capacity to serve as a crucial process validation check within the laboratory validation workflow.

实验室角度:确认手印增强试剂的完整性
验证在法医学中尤为重要。法医实验室使用的每个过程都将经过验证,以确保其按预期运作。有些设备(硬件)很容易验证,这将定期进行。然而,许多常用的手印增强试剂,如茚三酮和1,2-茚二酮,没有明确定义和可靠的验证参数。为此,人工手印溶液,特别是氨基酸溶液,已被研究作为一种受控验证方法,通过沉积到底物上。虽然氨基酸试剂很重要,但还有更广泛的潜在手印成分(目标)需要在法医实验室使用其他增强试剂。本文提出的工作旨在通过探索沉积皮脂溶液基质的可能性来扩展氨基酸打印的概念,从而促进油-红- o和物理显影剂等试剂的测试。此外,我们提出了一种方法,通过开发一种方法,使氰基丙烯酸酯发烟技术的工艺验证变得容易,从而扩展了多孔基材的指纹增强试剂的能力。这些简单而有效的解决方案有能力作为实验室验证工作流程中的关键工艺验证检查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Science & Justice
Science & Justice 医学-病理学
CiteScore
4.20
自引率
15.80%
发文量
98
审稿时长
81 days
期刊介绍: Science & Justice provides a forum to promote communication and publication of original articles, reviews and correspondence on subjects that spark debates within the Forensic Science Community and the criminal justice sector. The journal provides a medium whereby all aspects of applying science to legal proceedings can be debated and progressed. Science & Justice is published six times a year, and will be of interest primarily to practising forensic scientists and their colleagues in related fields. It is chiefly concerned with the publication of formal scientific papers, in keeping with its international learned status, but will not accept any article describing experimentation on animals which does not meet strict ethical standards. Promote communication and informed debate within the Forensic Science Community and the criminal justice sector. To promote the publication of learned and original research findings from all areas of the forensic sciences and by so doing to advance the profession. To promote the publication of case based material by way of case reviews. To promote the publication of conference proceedings which are of interest to the forensic science community. To provide a medium whereby all aspects of applying science to legal proceedings can be debated and progressed. To appeal to all those with an interest in the forensic sciences.
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