Comparison of Risk Factors & Angiographic Profiles between Young Patients with ST Segment Elevation Myocardial Infarction and Non-ST Segment Elevation Myocardial Infarction

Bangladesh Heart Journal Pub Date : 2021-10-31 DOI:10.3329/bhj.v36i2.56038

Sayeedur Rahman Khan, Fazila-tun-nesa Malik, M. Ahmed, A. Biswas, Mainul Islam, Bivash Kumer Sheel, Sharmin Tahmina Khan, H. Iqbal, Md. Rafiqul Islam

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引用次数: 1

Abstract

Background: Coronary artery disease is the leading cause of death in the world. Advancing age is a well-recognized risk factor for acute myocardial infarction (AMI). Myocardial infarction is less common in young adults. Prevalence of acute coronary syndrome in young individuals is increasing progressively. These patients have different risk profile, presentation and prognosis. Early recognition and risk factor modification in this population sub-set is of key importance. Objectives: The purpose of the present study was to determine the differences in risk factors and coronary angiographic profile of young patients with ST-segment elevated myocardial infarction (STEMI) vs. those with non-ST-segment elevated myocardial infarction (NSTEMI). Methods: In this cross sectional analytical study total 135 patients (70 STEMI and 65 NSTEMI) aged ≤45 years were enrolled to see the differences of risk factors and angiographic profile. Results: The mean age of the study population was 39.39±5.12 years and the study showed male predominance (90.40 % was male and 9.60 % was female). Smoking/tobacco consumption was significantly higher in STEMI patients, whereas diabetes mellitus and hypertension were more prevalent in NSTEMI patients. The frequency of single vessel disease and involvement of left anterior descending artery was significantly higher in young STEMI patients. In case of young NSTEMI patients frequency of triple vessel disease, noncritical coronary artery disease and involvement of left circumflex coronary was significantly higher. The frequency of double vessel disease and involvement of left main coronary artery was also nonsignificantly higher in young NSTEMI patients. There was no significant difference regarding involvement of right coronary artery. Conclusion: There are significant differences between young STEMI and young NSTEMI patients in respect to risk factors and angiographic profile. Key words: Young patient, STEMI, NSTEMI, Risk factors, Coronary angiographic profile. Bangladesh Heart Journal 2021; 36(2): 124-132

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年轻ST段抬高型心肌梗死与非ST段抬高型心肌梗死的危险因素及血管造影比较

背景:冠状动脉疾病是世界上导致死亡的主要原因。高龄是急性心肌梗死(AMI)的一个公认的危险因素。心肌梗塞在年轻人中不太常见。急性冠状动脉综合征在年轻人中的患病率正在逐渐增加。这些患者有不同的风险特征、表现和预后。这一人群的早期识别和危险因素的改变是至关重要的。目的:本研究的目的是确定年轻st段抬高型心肌梗死(STEMI)患者与非st段抬高型心肌梗死(NSTEMI)患者的危险因素和冠状动脉造影特征的差异。方法:本横断面分析研究共纳入135例年龄≤45岁的STEMI和NSTEMI患者(70例和65例)，观察危险因素和血管造影特征的差异。结果:研究人群平均年龄为39.39±5.12岁，以男性为主(男性占90.40%，女性占9.60%)。吸烟/烟草消费在STEMI患者中明显更高，而糖尿病和高血压在NSTEMI患者中更为普遍。年轻STEMI患者出现单血管病变和累及左前降支的频率明显高于年轻STEMI患者。年轻NSTEMI患者出现三支血管病变、非危重性冠状动脉病变和左旋冠状动脉受累的频率明显较高。年轻NSTEMI患者出现双支病变和左主干冠状动脉受累的频率也无显著性增高。两组在右冠状动脉受累方面无显著差异。结论:年轻STEMI患者与年轻NSTEMI患者在危险因素和血管造影方面存在显著差异。关键词:年轻患者，STEMI，非STEMI，危险因素，冠状动脉造影孟加拉国心脏杂志2021;36 (2): 124 - 132

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Bangladesh Heart Journal

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