Minimal Intubating Dose of Succinylcholine: A Comparative Study of 0.4, 0.5 and 0.6 mg/kg Dose

Ajit Gupta, Saurav Shekhar, Ankesh, Rajesh Kumar, Jay Prakash
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Abstract

Muscle relaxants are integral part of modern balanced anesthesia and succinylcholine, a depolarizing drug, is in use despite its adverse effects. The excellent intubating condition, fastest onset and shortest duration of action make it an excellent choice for anesthesiologists. The conventional dose of 1.5-2 mg/kg is commonly used for obtaining relaxation for intubation. This study was conducted with much smaller dose of succinylcholine as 0.4, 0.5 and 0.6 mg/kg to evaluate the acceptable intubating dose at 60 seconds, which was unlikely to have any untoward/side effects.
琥珀酰胆碱最小插管剂量:0.4、0.5和0.6 mg/kg剂量的比较研究
肌肉松弛剂是现代平衡麻醉的组成部分,琥珀酰胆碱是一种去极化药物,尽管有副作用,但仍在使用。良好的插管条件、最快的起效时间和最短的作用时间使其成为麻醉师的最佳选择。常规剂量1.5-2 mg/kg通常用于获得插管放松。本研究以0.4、0.5和0.6 mg/kg的小剂量琥珀胆碱进行,以评估60秒可接受的插管剂量,不太可能产生任何不良反应/副作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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