The Evaluation of Relationship Between Monocyte/High-Density Lipoprotein Ratio (MHR) and COVID-19

Konuralp Tıp Dergisi Pub Date : 2022-06-19 DOI:10.18521/ktd.1099432

Belgin Coşkun, M. Ayhan, E. M. Saricaoğlu, Rahmet Güner, E. Akıncı, T. Buzgan, B. Kayaaslan, A. Aypak, Ayşe Yasemin Tezer Tekçe, I. Hasanoğlu, A. Kaya Kalem, F. Eser, Y. Aybar Bilir, B. Özdemir

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Abstract

Objective: Early diagnosis is important for severe diseases in COVID-19. Monocyte/high dansity lipoprotein ratio (MHR) is a new prognostic marker indicating inflammation. We aimed to investigate the relationship between MHR and diseases severity in COVID-19. Materials and Methods: Patients with laboratory confirmed COVID-19, were retrospectively analyzed. Clinical symptoms, signs and laboratory data on the first day of hospitalization were obtained from medical records of hospital. The clinical data of 301 patients were included in study. Cases were diagnosed on the basis of interim guidance of World Health Organization (WHO). Patients were classified into two groups as non-severe COVID-19 and severe COVID-19. MHR were calculated with laboratory data on the first day of hospitalization. The relationship between MHR level and COVID-19 severity was evaluated. Statistical analysis of the data was performed by using SPSS 25 (SPSS Inc., Chicago, IL, USA) package program. Statistical significance level was accepted as p

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单核细胞/高密度脂蛋白比值(MHR)与COVID-19关系的评价

目的:对新冠肺炎重症患者早期诊断具有重要意义。单核细胞/高密度脂蛋白比值(MHR)是一种新的炎症预后指标。我们的目的是调查COVID-19中MHR与疾病严重程度的关系。材料与方法:对实验室确诊的COVID-19患者进行回顾性分析。入院第一天的临床症状、体征和实验室资料来源于医院病历。纳入301例患者的临床资料。病例诊断依据世界卫生组织(WHO)临时指南。将患者分为非重症和重症两组。根据住院第一天的实验室数据计算MHR。评估MHR水平与COVID-19严重程度的关系。采用SPSS 25 (SPSS Inc.， Chicago, IL, USA)软件包程序对数据进行统计分析。统计学显著性水平为p

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