An Early Robot Architecture for Cancer Healing

M. Abbas
{"title":"An Early Robot Architecture for Cancer Healing","authors":"M. Abbas","doi":"10.4018/jcmam.2011100103","DOIUrl":null,"url":null,"abstract":"Treating cancer tumors is a main goal of cancer research. The author of this paper identifies a new manner to treat cancer tumors more effectively using a recommended architecture of a nanorobot called CANBOT. It contains a number of nano-components: an actuator, temperature sensor, chemical sensor, and microcontroller. CANBOT starts its role by moving toward the tumor cells using the actuator. It senses the tumor cell by capturing its image and sensing its chemicals by the chemical sensor. When CANBOT distinguishes the tumor, it verifies the survival of the tumor cells by its temperature sensor. CANBOT increases the temperature of the tumor cell through the warmer. Sensing of the cancer chemicals starts over to detect the remaining existence of cancer cells. The suggested nanorobot injects the cell with the drug from a tiny tank throughout a nano pump with a small pine needle. A nano-microcontroller controls the mechanism of CANBOT formative the role of each one and the appropriate sequences. The position of the proposed nanorobot is simulated with reference to the position of the tumor using an analytical model. The conclusion is drawn that destroying the tumor requires instilling the robot into the cancer tumor directly for effective treatment. DOI: 10.4018/jcmam.2011100103 58 International Journal of Computational Models and Algorithms in Medicine, 2(4), 57-71, October-December 2011 Copyright © 2011, IGI Global. Copying or distributing in print or electronic forms without written permission of IGI Global is prohibited. Shirinzadeh, Freitas, & Kretly, 2007; Sierra, Weir, & Jones, 2005; Cavalcanti & Freitas, 2005; Mathieu, Martel, Yahia, Soulez, & Beaudoin, 2005; Behkam & Sitti, 2006; Xi, Schmidt, & Montemagno, 2005; Lee, Mahapatro, Caron, Requicha, Stauffer, Thompson, & Zhou, 2006; Fukuda, Kawamoto, Arai, & Matsuura, 1995; Freitas, 2005; Patel, Patel, Patel, Patel, & Patel, 2006; Ikeda, Arai, Fukuda, Kim, Negoro, Irie, & Takahashi, 2005; Xu, Vijaykrishnan, Xie, & Irwin, 2004; Park, Lee, & Lee, 2005; Couvreur & Vauthier, 2006; Gao, Wolfgang, Neschen, Morino, Horvath, Shulman, & Fu, 2004). The main objective of this paper is to match targeted therapies to cancer patients resourcefully and untimely using nanorobots. And the differentiated goal is to be able to abnegate tumor tissue in such a way as to abbreviate the bet of causing or allocating a recurrence of the growth in the body. The approach is conscious to be able to treat tumors that cannot be gained access via conventional surgery, such as abysmal brain tumors. Nanorobotics is the appearing technology area beginning apparatuses or robots whose components are at or access to the scale of a nanometer. More characteristically, nanorobotics refers to the nanotechnology engineering discipline of designing and creating nanorobots, with appliances ranging in amplitude from 0.110 micrometers and combined of nanoscale or molecular constituents. Nanomachines are amply in the research-and-development phase, although any primitive molecular machines have been analyzed. An archetypal is a sensor having a switch about 1.5 nanometers across, capable of counting specific molecules in a chemical archetypal. The first useful applications of nanomachines might be in medical technology, identify and destroy cancer cells (Cavalcanti, Shirinzadeh, Fukuda, & Ikeda, 2007; Leary, Liu, & Apuzzo, 2006; Boning, 2009; Boning, Ono, Nohara, & Dubowsky, 2008; Cavalcanti, Shirinzadeh, Freitas, & Kretly, 2007; Sierra, Weir, & Jones, 2005; Cavalcanti & Freitas, 2005; Mathieu, Martel, Yahia, Soulez, & Beaudoin, 2005; Behkam & Sitti, 2006; Xi, Schmidt, & Montemagno, 2005; Lee, Mahapatro, Caron, Requicha, Stauffer, Thompson, & Zhou, 2006; Fukuda, Kawamoto, Arai, & Matsuura, 1995; Freitas, 2005; Patel, Patel, Patel, Patel, & Patel, 2006; Ikeda, Arai, Fukuda, Kim, Negoro, Irie, & Takahashi, 2005; Xu, Vijaykrishnan, Xie, & Irwin, 2004; Park, Lee, & Lee, 2005; Couvreur & Vauthier, 2006; Gao, Wolfgang, Neschen, Morino, Horvath, Shulman, & Fu, 2004). Nanorobots interact with the cancer cells and based on molecular levels. The main component of the aimed nanorobot architecture is allotted in Section 2. The accomplished architecture design and the behavior of the proposed nanorobot is pioneered in Section 3. In Section 4 a verification of the proposed algorithms is presented. Section 5 demonstrates the system simulation and the results accrediting to the amplitudinous positions of the proposed nanorobot and the tumor. 2. LITERATURE REVIEW Previous researches presented the active components needed in our proposed nanorobot architecture. The proposed architecture consists of number of nano-components: a chemical sensor, a temperature sensor, an actuator and a micocontroller. These main components collaborate to achieve the goals of early detection and treatment of cancer tumor. The next subsections give a brief depiction about the structure and the functionality of these components. 2.1. Chemical Sensor The proposed nanorobot architecture uses the chemical sensors introduced in Cho, Lee, Kong, and Chandrakasan (2007). The basic idea of this type of chemical sensors is to source prearranged current to the carbon nanotube CNT sensors, and read the voltage residential across the sensors. This structural design is striking because the crossing point can vary the measurement ruling by changing the input current. This idea can be comprehensive over a proper current range to accomplish the necessary dynamic range since the system only needs 2% measurement precision across the preferred 13 more pages are available in the full version of this document, which may be purchased using the \"Add to Cart\" button on the product's webpage: www.igi-global.com/article/early-robot-architecture-cancerhealing/67530?camid=4v1 This title is available in InfoSci-Journals, InfoSci-Journal Disciplines Medicine, Healthcare, and Life Science. Recommend this product to your librarian: www.igi-global.com/e-resources/libraryrecommendation/?id=2","PeriodicalId":162417,"journal":{"name":"Int. J. Comput. Model. 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引用次数: 3

Abstract

Treating cancer tumors is a main goal of cancer research. The author of this paper identifies a new manner to treat cancer tumors more effectively using a recommended architecture of a nanorobot called CANBOT. It contains a number of nano-components: an actuator, temperature sensor, chemical sensor, and microcontroller. CANBOT starts its role by moving toward the tumor cells using the actuator. It senses the tumor cell by capturing its image and sensing its chemicals by the chemical sensor. When CANBOT distinguishes the tumor, it verifies the survival of the tumor cells by its temperature sensor. CANBOT increases the temperature of the tumor cell through the warmer. Sensing of the cancer chemicals starts over to detect the remaining existence of cancer cells. The suggested nanorobot injects the cell with the drug from a tiny tank throughout a nano pump with a small pine needle. A nano-microcontroller controls the mechanism of CANBOT formative the role of each one and the appropriate sequences. The position of the proposed nanorobot is simulated with reference to the position of the tumor using an analytical model. The conclusion is drawn that destroying the tumor requires instilling the robot into the cancer tumor directly for effective treatment. DOI: 10.4018/jcmam.2011100103 58 International Journal of Computational Models and Algorithms in Medicine, 2(4), 57-71, October-December 2011 Copyright © 2011, IGI Global. Copying or distributing in print or electronic forms without written permission of IGI Global is prohibited. Shirinzadeh, Freitas, & Kretly, 2007; Sierra, Weir, & Jones, 2005; Cavalcanti & Freitas, 2005; Mathieu, Martel, Yahia, Soulez, & Beaudoin, 2005; Behkam & Sitti, 2006; Xi, Schmidt, & Montemagno, 2005; Lee, Mahapatro, Caron, Requicha, Stauffer, Thompson, & Zhou, 2006; Fukuda, Kawamoto, Arai, & Matsuura, 1995; Freitas, 2005; Patel, Patel, Patel, Patel, & Patel, 2006; Ikeda, Arai, Fukuda, Kim, Negoro, Irie, & Takahashi, 2005; Xu, Vijaykrishnan, Xie, & Irwin, 2004; Park, Lee, & Lee, 2005; Couvreur & Vauthier, 2006; Gao, Wolfgang, Neschen, Morino, Horvath, Shulman, & Fu, 2004). The main objective of this paper is to match targeted therapies to cancer patients resourcefully and untimely using nanorobots. And the differentiated goal is to be able to abnegate tumor tissue in such a way as to abbreviate the bet of causing or allocating a recurrence of the growth in the body. The approach is conscious to be able to treat tumors that cannot be gained access via conventional surgery, such as abysmal brain tumors. Nanorobotics is the appearing technology area beginning apparatuses or robots whose components are at or access to the scale of a nanometer. More characteristically, nanorobotics refers to the nanotechnology engineering discipline of designing and creating nanorobots, with appliances ranging in amplitude from 0.110 micrometers and combined of nanoscale or molecular constituents. Nanomachines are amply in the research-and-development phase, although any primitive molecular machines have been analyzed. An archetypal is a sensor having a switch about 1.5 nanometers across, capable of counting specific molecules in a chemical archetypal. The first useful applications of nanomachines might be in medical technology, identify and destroy cancer cells (Cavalcanti, Shirinzadeh, Fukuda, & Ikeda, 2007; Leary, Liu, & Apuzzo, 2006; Boning, 2009; Boning, Ono, Nohara, & Dubowsky, 2008; Cavalcanti, Shirinzadeh, Freitas, & Kretly, 2007; Sierra, Weir, & Jones, 2005; Cavalcanti & Freitas, 2005; Mathieu, Martel, Yahia, Soulez, & Beaudoin, 2005; Behkam & Sitti, 2006; Xi, Schmidt, & Montemagno, 2005; Lee, Mahapatro, Caron, Requicha, Stauffer, Thompson, & Zhou, 2006; Fukuda, Kawamoto, Arai, & Matsuura, 1995; Freitas, 2005; Patel, Patel, Patel, Patel, & Patel, 2006; Ikeda, Arai, Fukuda, Kim, Negoro, Irie, & Takahashi, 2005; Xu, Vijaykrishnan, Xie, & Irwin, 2004; Park, Lee, & Lee, 2005; Couvreur & Vauthier, 2006; Gao, Wolfgang, Neschen, Morino, Horvath, Shulman, & Fu, 2004). Nanorobots interact with the cancer cells and based on molecular levels. The main component of the aimed nanorobot architecture is allotted in Section 2. The accomplished architecture design and the behavior of the proposed nanorobot is pioneered in Section 3. In Section 4 a verification of the proposed algorithms is presented. Section 5 demonstrates the system simulation and the results accrediting to the amplitudinous positions of the proposed nanorobot and the tumor. 2. LITERATURE REVIEW Previous researches presented the active components needed in our proposed nanorobot architecture. The proposed architecture consists of number of nano-components: a chemical sensor, a temperature sensor, an actuator and a micocontroller. These main components collaborate to achieve the goals of early detection and treatment of cancer tumor. The next subsections give a brief depiction about the structure and the functionality of these components. 2.1. Chemical Sensor The proposed nanorobot architecture uses the chemical sensors introduced in Cho, Lee, Kong, and Chandrakasan (2007). The basic idea of this type of chemical sensors is to source prearranged current to the carbon nanotube CNT sensors, and read the voltage residential across the sensors. This structural design is striking because the crossing point can vary the measurement ruling by changing the input current. This idea can be comprehensive over a proper current range to accomplish the necessary dynamic range since the system only needs 2% measurement precision across the preferred 13 more pages are available in the full version of this document, which may be purchased using the "Add to Cart" button on the product's webpage: www.igi-global.com/article/early-robot-architecture-cancerhealing/67530?camid=4v1 This title is available in InfoSci-Journals, InfoSci-Journal Disciplines Medicine, Healthcare, and Life Science. Recommend this product to your librarian: www.igi-global.com/e-resources/libraryrecommendation/?id=2
用于癌症治疗的早期机器人架构
治疗癌症肿瘤是癌症研究的主要目标。这篇论文的作者确定了一种新的方法来治疗癌症肿瘤更有效地使用一种被称为CANBOT的纳米机器人的推荐架构。它包含许多纳米组件:执行器,温度传感器,化学传感器和微控制器。CANBOT的作用开始于利用致动器向肿瘤细胞移动。它通过捕捉肿瘤细胞的图像来感知肿瘤细胞,并通过化学传感器感知肿瘤细胞的化学成分。当CANBOT区分肿瘤时,它通过其温度传感器来验证肿瘤细胞的存活。CANBOT通过加热器提高肿瘤细胞的温度。对癌症化学物质的感知重新开始,以检测癌细胞的残余存在。这个提议的纳米机器人用一根小松针将药物从一个小罐子里通过一个纳米泵注入细胞。用纳米微控制器控制CANBOT的作用机制,形成每个CANBOT的作用和适当的序列。利用解析模型,参照肿瘤的位置对所提出的纳米机器人的位置进行了模拟。得出结论,摧毁肿瘤需要将机器人直接注入肿瘤中进行有效治疗。DOI: 10.4018 / jcmam。2011100103 58 International Journal of Computational Models and Algorithms in Medicine, 2(4), 57-71, October-December版权所有©2011,IGI Global。未经IGI Global书面许可,禁止以印刷或电子形式复制或分发。Shirinzadeh, Freitas, & Kretly, 2007;Sierra, Weir, & Jones, 2005;卡瓦尔康蒂和弗雷塔斯,2005;Mathieu, Martel, Yahia, Soulez, & Beaudoin, 2005;Behkam & Sitti, 2006;Lee, Mahapatro, Caron, Requicha, Stauffer, Thompson, & Zhou, 2006;Fukuda, Kawamoto, Arai, & Matsuura, 1995;Freitas, 2005;帕特尔,帕特尔,帕特尔,帕特尔,&帕特尔,2006;池田,新井,福田,金,内格罗,Irie,高桥,2005;Xu, Vijaykrishnan, Xie, & Irwin, 2004;Park, Lee, & Lee, 2005;科维诺&沃蒂耶,2006;Gao, Wolfgang, Neschen, Morino, Horvath, Shulman, & Fu, 2004)。本文的主要目的是利用纳米机器人将靶向治疗与癌症患者进行匹配。分化的目标是能够以这样一种方式消除肿瘤组织,从而缩短导致或分配体内生长复发的风险。这种方法能够治疗传统手术无法治疗的肿瘤,如恶性脑肿瘤。纳米机器人是新兴的技术领域,其组成部分达到或接近纳米尺度的设备或机器人。更具体地说,纳米机器人是指设计和制造纳米机器人的纳米技术工程学科,其应用范围从0.110微米到纳米尺度或分子成分的组合。尽管任何原始分子机器都已被分析过,但纳米机器仍处于研究和开发阶段。一个原型是一个传感器,有一个大约1.5纳米宽的开关,能够计数化学原型中的特定分子。纳米机器的第一个有用的应用可能是在医疗技术中,识别和摧毁癌细胞(Cavalcanti, Shirinzadeh, Fukuda, & Ikeda, 2007;Leary, Liu, & Apuzzo, 2006;去骨,2009;Boning, Ono, Nohara, & Dubowsky, 2008;卡瓦尔康蒂,Shirinzadeh, Freitas, & Kretly, 2007;Sierra, Weir, & Jones, 2005;卡瓦尔康蒂和弗雷塔斯,2005;Mathieu, Martel, Yahia, Soulez, & Beaudoin, 2005;Behkam & Sitti, 2006;Lee, Mahapatro, Caron, Requicha, Stauffer, Thompson, & Zhou, 2006;Fukuda, Kawamoto, Arai, & Matsuura, 1995;Freitas, 2005;帕特尔,帕特尔,帕特尔,帕特尔,&帕特尔,2006;池田,新井,福田,金,内格罗,Irie,高桥,2005;Xu, Vijaykrishnan, Xie, & Irwin, 2004;Park, Lee, & Lee, 2005;科维诺&沃蒂耶,2006;Gao, Wolfgang, Neschen, Morino, Horvath, Shulman, & Fu, 2004)。纳米机器人在分子水平上与癌细胞相互作用。目标纳米机器人架构的主要组成部分在第2节中分配。完成的架构设计和提议的纳米机器人的行为是在第3节开创。在第4节中,提出了对所提出算法的验证。第5节演示了系统仿真和结果,证明了所提出的纳米机器人和肿瘤的振幅位置。2. 文献综述先前的研究介绍了我们提出的纳米机器人结构所需的活性成分。所提出的架构由许多纳米组件组成:化学传感器,温度传感器,执行器和微控制器。这些主要组成部分相互协作,以实现早期发现和治疗癌症肿瘤的目标。接下来的小节将简要介绍这些组件的结构和功能。2.1.
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