Anesthesia in severe preeclampsia

Jayavelan Ramkumar, Nidhi Sharma
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Abstract

The word “Preeclampsia” is derived from the Greek word Eklampsis meaning “lightening” or “convulsions”. A pregnancy with preeclampsia whose hypertension has been treated ante partum generally present for delivery with contracted plasma volume, normal or increased cardiac output, vasoconstriction, and hyper dynamic left ventricular function. There may also be a coexisting left ventricular systolic and diastolic dysfunction. Other problems are increased airway edema, decreased glomerular filtration, platelet dysfunction, or a spectrum of hemostatic derangements (the exaggerated hypercoagulable state).1 In severe preeclampsia there is chronic placental hypo perfusion.2 The uteroplacental circulation is not auto regulated and the fetus may poorly tolerate any further decline in perfusion. Thus the primary peripartum goals in the severely preeclampsia parturient are the optimization of maternal blood pressure, cardiac output, and uteroplacental perfusion and the prevention of seizures and stroke. The main concerns to the anaesthetist are an edematous airway, dysfunction of the cardio respiratory system, dysfunction of cerebro-vascular system and the dysfunction of coagulation system.3
重度子痫前期的麻醉
“先兆子痫”这个词来源于希腊语Eklampsis,意思是“闪电”或“抽搐”。产前高血压治疗过的子痫前期妊娠,分娩时血浆量收缩,心排血量正常或增加,血管收缩,左心室功能亢进。也可能同时存在左心室收缩和舒张功能不全。其他问题包括气道水肿增加、肾小球滤过减少、血小板功能障碍或一系列止血功能紊乱(高凝状态夸大)重度子痫前期存在慢性胎盘灌注不足子宫胎盘循环不是自动调节的,胎儿可能难以忍受任何进一步的灌注下降。因此,重度子痫前期围生期的首要目标是优化产妇血压、心排血量和子宫胎盘灌注,预防癫痫发作和脑卒中。麻醉师主要关心的是气道水肿、心肺系统功能障碍、脑血管系统功能障碍和凝血系统功能障碍
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