Gentimacin Injection Induced Digital Necrosis in a 32 -Year Old Apprentice: A Case Report

A. Udo
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Abstract

Gentamicin is a type of aminoglycoside produced by the fermentation of bacteria widely present in the environment. Because of its widespread use and abuse, their toxic effects have become more obvious and sometimes bizarre. Toxic effects involve the kidneys, ears and rarely neuromuscular junction as well as neurovascular bundles leading to ischemia and tissue necrosis. I present a 32-year old apprentice who developed bluish to black discoloration of the terminal phalanx of the index, middle, ring and little fingers of both hands following several injections of gentamicin. Digital necrosis arising from injection of gentamicin is rare in the scientific literature. Adverse effects of aminoglycosides can be prevented through proper regulation of its use.
32岁学徒注射庆大霉素致指骨坏死1例
庆大霉素是一种氨基糖苷,由广泛存在于环境中的细菌发酵产生。由于其广泛使用和滥用,其毒性作用变得更加明显,有时甚至是奇怪的。毒性作用累及肾脏、耳朵,很少累及神经肌肉连接处和神经血管束,导致缺血和组织坏死。我报告了一名32岁的学徒,他在注射庆大霉素几次后,双手的食指、中指、无名指和小指的末端指骨出现了蓝色到黑色的变色。在科学文献中,因注射庆大霉素引起的指部坏死是罕见的。氨基糖苷的不良反应可以通过适当的使用规范来预防。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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