Helicobacter Pylori Infection and Risk of Variceal Bleeding among Patients with Liver Cirrhosis

Abstract

Inflammatory changes in the stomach caused by Helicobacter pylori indirectly and directly affect liver function. Moreover, the bacteria may worsen the course of the liver cirrhosis. The incidence of portal hypertension and esophageal varices correlates with the incidence of H. pylori infection. This study aims to detect H. pylori infection among patients with liver cirrhosis correlation with the degree of liver injury according to Child–Pugh classification and the stage of esophageal varices and its bleeding. This study was conducted in Hepatology and Gastroenterology and Infectious diseases of Al_Azhar medical Department from December 2018 till November 2020. 50 patients were included in bleeder group 32 patient had H.pylori and 18 patient negative H.pylori. 50 patient were included in non_bleeder group 28 patient had H.pylori and 22 patient were negative H.pylori. our results indicated statistically significant decrease in the prevalence of H. pylori infection among the bleeder group.